Incidence and Risk Factors of Gastric Retention Associated With Enteral Nutrition: A Systematic Review and Meta‐Analysis.

Background: Gastric retention is a common complication in enteral nutrition, which may lead to interruption of nutrition, malnutrition, electrolyte imbalance and other problems. Up‐to‐date knowledge of its incidence and influencing factors is crucial for optimal management strategies of enteral nutr...

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Publicado en:International Journal of Nursing Practice (John Wiley & Sons, Inc.) Vol. 32; no. 4; pp. 1 - 15
Autores principales: Li, Tiantian, Qu, Nan, Zhang, Lifeng, Liu, Xingyu, Cui, Liping, Gao, Pei
Formato: meta analysis research systematic review tables/charts Journal Article
Publicado: John Wiley & Sons, Inc. Aug2026
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Aug2026
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      pub: John Wiley & Sons, Inc.
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        atl: Incidence and Risk Factors of Gastric Retention Associated With Enteral Nutrition: A Systematic Review and Meta‐Analysis.
      aug:
        au:
          Li, Tiantian
          Qu, Nan
          Zhang, Lifeng
          Liu, Xingyu
          Cui, Liping
          Gao, Pei
        affil: School of Nursing, Shanxi University of Chinese Medicine, Jinzhong Shanxi,, China
      sug:
        subj:
          Gastroparesis Epidemiology
          Gastroparesis Risk Factors
          Enteral Nutrition Adverse Effects
          Risk Assessment
          Human
          Meta Analysis
          Systematic Review
          PubMed
          Embase
          Cochrane Library
          Confidence Intervals
          Data Analysis Software
          Incidence
          Probiotics
          Hyperglycemia
          Respiration, Artificial
          Hypokalemia
          Constipation
          Hypotension
          Coinfection
          Cerebral Infarction
          Esophageal Neoplasms
          Checklists
      ab: Background: Gastric retention is a common complication in enteral nutrition, which may lead to interruption of nutrition, malnutrition, electrolyte imbalance and other problems. Up‐to‐date knowledge of its incidence and influencing factors is crucial for optimal management strategies of enteral nutrition. Aim: This study aimed to conduct a systematic review and meta‐analysis to quantify the incidence of retention of gastric contents in patients receiving enteral feeding and to identify significant influencing factors. Design: This study is a systematic review and meta‐analysis. Data Sources and Review Methods: Using established methods and searching from database inception to 18 May 2025, we searched CNKI, Wanfang Data, CBM, VIP, PubMed, Web of Science, EMBASE and The Cochrane Library. RevMan 5.4 software was used to perform the meta‐analysis. Results: A meta‐analysis of 14 studies involving 2642 patients receiving enteral nutrition reported a 32.0% incidence of gastric retention. Nineteen factors associated with gastric retention were identified. Notably, descriptive analyses indicated that early initiation of enteral nutrition (OR = 0.37) and concomitant use of probiotics (OR = 0.22) were protective against the development of gastric retention. Conclusion: Findings support clinicians and nurses in more accurately identifying high‐risk patients and formulating targeted intervention strategies based on the identified risk factors. Summary: What Is Already Known About This Topic? Gastric retention associated with enteral nutrition is a clinical issue affecting multiple systems, including digestion, metabolism and immunity, which seriously influences patients' prognosis and quality of life.The incidence of gastric retention in enteral nutrition is relatively high, and the influencing factors are diverse but lack consistency across studies.What This Paper Adds? Review findings demonstrated a 32% incidence of gastric retention with enteral nutrition.This review found the following influential factors: Glasgow Coma Score (GCS) ≤ 8, age ≥ 50 years, hypokalaemia, constipation, reduced bowel sounds, hypotension, co‐infections, electrolyte imbalances, hyperglycaemia, mechanical ventilation therapy and hypothermia therapy.Protective factors include early implementation of enteral nutrition and combined use of probiotics.The Implications of This Paper: Systematic evaluation of the incidence and determinants of the ileus in enteral nutrition is crucial, as it directly influences the effectiveness of nutritional support and clinical prognosis.Review findings are highly heterogeneous; cautious interpretation is needed, and future high‐quality, multicentre RCTs are required to clarify independent factors.
      pubtype: Academic Journal
      doctype:
        meta analysis
        research
        systematic review
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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