Association between Weight Loss and Survival Outcomes in Patients with Esophageal Cancer: A Meta-Analysis.
Weight loss is a common symptom in patients with esophageal cancer and can negatively impact survival outcomes. This meta-analysis aimed to systematically evaluate the relationship between weight loss and survival outcomes in individuals diagnosed with esophageal cancer. We conducted a comprehensive...
| Publicado en: | Nutrition & Cancer Vol. 78; no. 8/9; pp. 584 - 593 |
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| Autores principales: | , , |
| Formato: | research systematic review tables/charts Journal Article |
| Publicado: |
Taylor & Francis Ltd
2026
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=196565297&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 196565297 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 01635581 7MS jtl: Nutrition & Cancer issn: 01635581 maglogo: N pubinfo: dt: 2026 vid: 78 iid: 8/9 pid: 377 pub: Taylor & Francis Ltd place: Philadelphia, Pennsylvania artinfo: ui: 196565297 196065318 196565297 196565297 10.1080/01635581.2026.2715798 196565297 ppf: 584 ppct: 9 formats: fmt: – @attributes: type: T – @attributes: type: P tig: atl: Association between Weight Loss and Survival Outcomes in Patients with Esophageal Cancer: A Meta-Analysis. aug: au: Jiang, Mei Zhang, Yueshi Fan, Yu affil: Outpatient Department of Cardiology, The Affiliated Hospital, Jiangsu University, Zhenjiang, Jiangsu, China sug: subj: Esophageal Neoplasms Mortality Weight Loss Survival Analysis Human Systematic Review PubMed Embase Meta Analysis Descriptive Statistics Progression-Free Survival Cancer Patients Confidence Intervals Overall Survival Age Factors Carcinoma, Squamous Cell Diagnosis Treatment Duration After Care ab: Weight loss is a common symptom in patients with esophageal cancer and can negatively impact survival outcomes. This meta-analysis aimed to systematically evaluate the relationship between weight loss and survival outcomes in individuals diagnosed with esophageal cancer. We conducted a comprehensive search of PubMed, Embase, and Web of Science for studies reporting the association between weight loss and overall survival or progression-free survival in patients with esophageal cancer. Pooled adjusted hazard ratios (HR) and 95% confidence intervals (CI) were calculated using a random-effects model. Eleven studies involving 3,566 esophageal cancer patients were included. The pooled results indicated that weight loss was significantly associated with poorer overall survival (HR 1.68; 95% CI 1.49–1.90) and progression-free survival (HR 1.61; 95% CI 1.39–1.86). Subgroup analyses revealed a numerically higher HR for overall survival in patients aged 60 years or younger, those assessed for weight loss during treatment, patients with a follow-up duration exceeding 36 months, and individuals diagnosed with squamous cell carcinoma. Weight loss was significantly associated with poorer overall survival in patients with esophageal cancer. Regarding progression-free survival, a preliminary pooled analysis based on only two studies suggested a potential association; however, this finding requires confirmation in future research. pubtype: Academic Journal doctype: meta analysis research systematic review tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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