Individuals with intellectual disability and complex epilepsy: a case study of diagnostic overshadowing.
People with intellectual disability have a higher prevalence of epilepsy, care complexity, comorbidity and polypharmacy than the general population. These patients are often found to be on multiple medications without a clear rationale for ongoing prescriptions. Recent evidence has highlighted the o...
| Publicado en: | British Journal of Nursing Vol. 35; no. 16; pp. 818 - 826 |
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| Autores principales: | , , , |
| Formato: | case study tables/charts Journal Article |
| Publicado: |
Mark Allen Holdings Limited
9/3/2026
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=196690659&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 196690659 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 09660461 GHD jtl: British Journal of Nursing issn: 09660461 maglogo: N pubinfo: dt: 9/3/2026 vid: 35 iid: 16 pid: 11383 pub: Mark Allen Holdings Limited artinfo: ui: 196690659 196690659 196690659 10.12968/bjon.2025.0427 196690659 ppf: 818 ppct: 8 formats: fmt: – @attributes: type: T – @attributes: type: P tig: atl: Individuals with intellectual disability and complex epilepsy: a case study of diagnostic overshadowing. aug: au: Boyle, Andrew Spassiani, Natasha Houghton, Valerie Paterson, Ruth affil: Lecturer, Edinburgh Napier University, Edinburgh, UK sug: subj: Intellectual Disability Drug Therapy Persons with Disabilities Lennox-Gastaut Syndrome Drug Therapy Polypharmacy Medication Management Seizures Etiology Iatrogenic Disease Prevention and Control Drug Interactions Anticonvulsants Administration and Dosage Anticonvulsants Blood Deprescribing Nursing Role Patient Advocacy Multidisciplinary Care Team Collaboration ab: People with intellectual disability have a higher prevalence of epilepsy, care complexity, comorbidity and polypharmacy than the general population. These patients are often found to be on multiple medications without a clear rationale for ongoing prescriptions. Recent evidence has highlighted the ongoing exposure to avoidable health inequalities and premature death in this population group, in which medicines management can play an influential role. This article aims to identify practical interventions to mitigate the risk of diagnostic overshadowing and health inequalities in individuals with intellectual disability and complex epilepsy. The discussion centres on a comprehensive retrospective analysis of the care outcomes experienced by an individual with a diagnosed epilepsy syndrome (Lennox-Gastaut syndrome). Rationalising medication is complex but can reduce the risk of drug interactions and adverse outcomes. Iatrogenic effects can be mistaken for physical health symptoms and confound care pathways. Systematic assessment and collaboration with appropriately experienced clinicians improves outcomes. Prospective therapeutic drug monitoring may have a role to play in mitigating adverse outcomes and diagnostic overshadowing in individuals with intellectual disability and complex epilepsy. pubtype: Academic Journal doctype: case study tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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