| Sumario: | Enhancing and aligning doctor–patient relationships is a perennial challenge in healthcare. The burgeoning role of digital medical popularization in medical services raises questions about its specific contributions to fostering harmonious interactions between doctors and patients. This qualitative study, employing in‐depth interviews and grounded theory methodologies, explores these dynamics. We engaged a total of 58 participants—comprising 13 doctors and 45 patients—from hospitals in Shanghai, selected via a snowball sampling method and adhering to predefined inclusion criteria. Data collection and analysis proceeded iteratively until theoretical saturation was achieved. Our findings indicate that the quality of doctor–patient relationships is intricately linked to the asymmetry in information exchange. Digital medical popularization exerts a positive influence by mitigating this asymmetry across three key dimensions: expertise knowledge, power distribution, and social support. Further analysis highlights that the precision of digital medical popularization and its efficacy in catalyzing patient action transformation are crucial for these processes. Consequently, we conclude that digital medical popularization significantly contributes to the harmony of doctor–patient relationships by addressing information asymmetry. There is an imperative need to concentrate on enhancing the accuracy of digital medical popularization and facilitating patients′ translation of digital information into concrete actions.
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