Visual versus automated CT perfusion for outcome prediction in anterior circulation stroke treated with mechanical thrombectomy.
The prognostic value of simple visual assessment of CT perfusion (CTP) for predicting clinical outcomes has already been demonstrated in stroke patients undergoing mechanical thrombectomy (MT). Automated software, however, has become the dominant method of CTP evaluation. The aim of the study was to...
| Publicado en: | Radiology & Oncology Vol. 60; no. 3; pp. 394 - 402 |
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| Autores principales: | , , , |
| Formato: | diagnostic images research tables/charts Journal Article |
| Publicado: |
Paradigm Publishing Services
Sep2026
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=196817787&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 196817787 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 13182099 39VO jtl: Radiology & Oncology issn: 13182099 maglogo: N pubinfo: dt: Sep2026 vid: 60 iid: 3 pid: 35924 pub: Paradigm Publishing Services artinfo: ui: 196817787 195706471 196817787 196817787 10.2478/raon-2026-0039 196817787 ppf: 394 ppct: 8 formats: tig: atl: Visual versus automated CT perfusion for outcome prediction in anterior circulation stroke treated with mechanical thrombectomy. aug: au: Rigler, Igor Gspan, Tina Longo, Alja Oblak, Janja Pretnar affil: Clinical Department of Vascular and Intensive Neurology Therapy, Neurology Clinic, University Medical Centre Ljubljana, Ljubljana, Slovenia sug: subj: Ischemic Stroke Surgery Thrombectomy Ischemic Stroke Prognosis Treatment Outcomes Evaluation Tomography, X-Ray Computed Methods Perfusion Imaging Image Processing, Computer Assisted Human Retrospective Design Record Review Computed Tomography Angiography Functional Status Descriptive Statistics Pearson's Correlation Coefficient Chi Square Test Scales ab: The prognostic value of simple visual assessment of CT perfusion (CTP) for predicting clinical outcomes has already been demonstrated in stroke patients undergoing mechanical thrombectomy (MT). Automated software, however, has become the dominant method of CTP evaluation. The aim of the study was to compare the prognostic accuracy of visually graded CTP maps with automated CTP analysis on clinical outcomes in anterior circulation stroke patients treated with MT. In the single centre we retrospectively analysed consecutive patients with anterior circulation large-vessel occlusion treated with MT. Baseline imaging included non-contrast brain CT, CT angiography (CTA) with collateral status (CS) and CTP. Time to peak (TTP) maps were visually graded on a four-level ordinal scale based on estimated penumbra. Automated CTP was processed with syngo.via (SYV) using default thresholds and classified on a comparable ordinal scale. The primary endpoint was favourable 90-day functional outcome (Rankin Scale (mRS) ≤ 3). We included 579 patients. Agreement between visual and automated CTP was fair (κ = 0.36). Both methods were significantly associated with favourable outcome (p < 0.01), with visual grading showing a slightly stronger association (Pearson χ2 = 30 vs. 22). In multivariable models, visual CTP remained an independent predictor, whereas automated CTP lost significance when CS was included. Visual CTP grading provided a slightly better prognostic performance than automated CTP. Visual CTP assessment is a simple, accessible and clinically meaningful tool for both treatment decision making and outcome prediction in anterior circulation stroke treated with MT. pubtype: Academic Journal doctype: diagnostic images research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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