Family functioning, social vulnerability, depression and frailty among older people with HIV: A structural equation modeling analysis.

• As older people with HIV face the combined pressures of aging and HIV, they may become less connected to the broader social environment, making family a critical source of support for coping with stress. • Family functioning serves as a kind of social support, helps individuals cope with the stres...

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Publicado en:Geriatric Nursing Vol. 72
Autores principales: Sun, Wenxiu, Pan, Yanyun, Tang, Jiajie, Arbing, Rachel H.A., Chen, Wei-Ti, Zhang, Lin
Formato: research Journal Article
Publicado: Elsevier B.V. Sep2026
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Sep2026
      vid: 72
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      pub: Elsevier B.V.
      place: New York, New York
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        196818688
        196818688
        196818688
        10.1016/j.gerinurse.2026.104189
        196818688
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        atl: Family functioning, social vulnerability, depression and frailty among older people with HIV: A structural equation modeling analysis.
      aug:
        au:
          Sun, Wenxiu
          Pan, Yanyun
          Tang, Jiajie
          Arbing, Rachel H.A.
          Chen, Wei-Ti
          Zhang, Lin
        affil: Department of Nursing, Shanghai Public Health Clinical Center, Fudan University, Shanghai, China
      sug:
        subj:
          HIV-Positive Persons Psychosocial Factors
          Family Functioning Evaluation
          Vulnerability Evaluation
          Social Isolation Evaluation
          Loneliness Evaluation
          Depression Complications
          Frailty Syndrome Risk Factors
          Risk Assessment
          Human
          Aged
          Aged, 80 and Over
          Structural Equation Modeling
          Mediation Analysis
          Correlational Studies
          Quantitative Studies
          Cross Sectional Studies
          China
          Data Analysis Software
          Descriptive Statistics
          Aged: 65+ years
          Aged, 80 & over
      ab: • As older people with HIV face the combined pressures of aging and HIV, they may become less connected to the broader social environment, making family a critical source of support for coping with stress. • Family functioning serves as a kind of social support, helps individuals cope with the stress and challenges posed by diseases and prevents the development of unhealthy emotions. • Social vulnerability has been shown to be associated with increased disruptions in family functioning. • This study shows that depression and social vulnerability (including social isolation and loneliness) mediate the relationship between family functioning and multidimensional frailty. • Family functioning significantly influences multidimensional frailty among older PWH, with social vulnerability and depression acting as mediating factors. This study explored the influence of family functioning on frailty among older people with HIV (PWH) and the mediating roles of social vulnerability and depression. A quantitative cross-sectional study. A cross-sectional survey of older PWH from December 2022 to October 2023 was carried out in Shanghai, China. Data on sociodemographics, family functioning, social vulnerability (social isolation and loneliness), depression and multidimensional frailty were gathered and analyzed by structural equation modeling (SEM). Analysis was performed via SPSS 24.0 and AMOS 23.0. Family functioning affects older PWH's frailty through three indirect paths: through the mediating role of social vulnerability and depression separately and through the chain-mediating role of both social vulnerability and depression. Family functioning in older PWH is associated with multidimensional frailty, which is mediated by social vulnerability and depression. Based on these findings, targeted interventions focusing on improving family functioning, reducing social vulnerability, and alleviating depression may effectively prevent and mitigate frailty, thereby promoting health and wellbeing among older PWH.
      pubtype: Academic Journal
      doctype:
        research
        Journal Article
      ougenre: Article
    language: English
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