Evaluation of the Prognostic Nutritional Index in Conjunction with Lung Cancer Stage and PET-CT SUVmax.
OBJECTIVE: Lung cancer is among the malignancies with the highest mortality rates globally, where nutritional and immune status significantly influence disease progression and prognosis. The study aimed to investigate the relationship of the prognostic nutritional index (PNI) with both the maximum s...
| Publicado en: | Thoracic Research & Practice Vol. 27; no. 5; pp. 294 - 300 |
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| Autores principales: | , , , , , , |
| Formato: | research tables/charts Journal Article |
| Publicado: |
Galenos Yayinevi Tic. LTD. STI
Sep2026
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=196825469&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 196825469 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 29799139 N9E4 jtl: Thoracic Research & Practice issn: 29799139 maglogo: N pubinfo: dt: Sep2026 vid: 27 iid: 5 pid: 28155 pub: Galenos Yayinevi Tic. LTD. STI artinfo: ui: 196825469 196825469 196825469 10.4274/ThoracResPract.2026.2026-4-7 196825469 ppf: 294 ppct: 6 formats: tig: atl: Evaluation of the Prognostic Nutritional Index in Conjunction with Lung Cancer Stage and PET-CT SUVmax. aug: au: Kaya, İlknur Erbay, Ümran Parspur, Şebnem Emine Marım, Feride Doğan, Mehmet Kaya, Şerife Kan, Jülide affil: Department of Pulmonology Kütahya Health Sciences University, Kütahya, Türkiye sug: subj: Lung Neoplasms Diagnosis Neoplasm Staging Nutritional Status Positron Emission Tomography Computed Tomography Methods Fludeoxyglucose F 18 Diagnostic Use Human Turkiye Male Female Retrospective Design Nonexperimental Studies Colleges and Universities Adult Middle Age Aged Aged, 80 and Over Descriptive Statistics Data Analysis Software Spearman's Rank Correlation Coefficient Kruskal-Wallis Test Comparative Studies Bronchoscopy Cancer Patients Tumor Markers, Biological Adult: 19-44 years Middle Aged: 45-64 years Aged: 65+ years Aged, 80 & over Male Female ab: OBJECTIVE: Lung cancer is among the malignancies with the highest mortality rates globally, where nutritional and immune status significantly influence disease progression and prognosis. The study aimed to investigate the relationship of the prognostic nutritional index (PNI) with both the maximum standardized uptake value (SUVmax), measured by positron emission tomography-computed tomography, and the clinical stage of lung cancer. MATERIAL AND METHODS: Patients who underwent fiberoptic bronchoscopy and were diagnosed with lung cancer at the Department of Pulmonology, Kütahya Health Sciences University, between January 1, 2022 and May 31, 2025, were retrospectively evaluated. A total of 241 patients diagnosed with lung cancer via bronchoscopy were evaluated; of these, 205 patients diagnosed with non-small-cell lung cancer (n = 205) were assessed according to stage. RESULTS: A total of 241 lung cancer patients were included; the mean age was 68.35±8.52 years and 95.0% were male. The mean PNI was 41.41±9.50 and the mean primary tumor SUVmax was 10.53±5.22. PNI and primary tumor SUVmax showed a very weak negative association that did not reach statistical significance (Spearman r = -0.127; P = 0.055). Clinical stage was positively associated with SUVmax (r = 0.253; P < 0.001) and negatively associated with PNI (r = -0.186; P = 0.007). CONCLUSION: Higher clinical stage was associated with higher primary tumor SUVmax and lower PNI. The association between PNI and SUVmax was weak and not statistically significant; therefore, it should not be considered clinically discriminative on its own. PNI may serve as an adjunctive indicator of nutritional and immune status, but prospective studies with survival outcomes and multivariable adjustment are required before it can be used as a prognostic or staging tool. pubtype: Academic Journal doctype: research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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