Correlations between fetal left ventricular Tei index and different hemodynamic parameters during middle and late pregnancy at high altitudes.
To compare fetal left ventricular Tei index (TI) values and hemodynamic correlations between high-altitude and low-altitude pregnancies, establishing an altitude-specific framework for fetal cardiac assessment. This prospective dual-group study enrolled 234 high-altitude and 252 low-altitude singlet...
| Publicado en: | Journal of Perinatal Medicine Vol. 54; no. 7; pp. 1174 - 1182 |
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| Autores principales: | , , |
| Formato: | diagnostic images research tables/charts Journal Article |
| Publicado: |
De Gruyter
Sep2026
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=196960240&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 196960240 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 03005577 0FP jtl: Journal of Perinatal Medicine issn: 03005577 maglogo: N pubinfo: dt: Sep2026 vid: 54 iid: 7 pid: 1734 pub: De Gruyter place: , <Blank> artinfo: ui: 196960240 194746349 196960240 196960240 10.1515/jpm-2025-0513 196960240 ppf: 1174 ppct: 8 formats: tig: atl: Correlations between fetal left ventricular Tei index and different hemodynamic parameters during middle and late pregnancy at high altitudes. aug: au: Ni, Jiao Chen, Hongjian Chen, Nianqiao affil: Department of Ultrasound, The Third People's Hospital of Yunnan, Kunming, China sug: subj: Fetal Heart Ultrasonography Heart Ventricle, Left Ultrasonography Ventricular Dysfunction, Left Ultrasonography Echocardiography, Doppler In Utero Hemodynamics Evaluation Altitude Pregnancy Trimester, Second Pregnancy Trimester, Third Fetal Monitoring Human Correlational Studies Fetus Female Adult Prospective Studies China Expectant Mothers Umbilical Arteries Middle Cerebral Artery Arteries Uterus Blood Supply Descriptive Statistics Gestational Age Fetal Anoxia Pregnancy Umbilical Veins Systole Diastole Ventricular Function, Left Evaluation Ultrasonography, Prenatal Comparative Studies Myocardial Contraction Evaluation Fetus, conception to birth Adult: 19-44 years Female ab: To compare fetal left ventricular Tei index (TI) values and hemodynamic correlations between high-altitude and low-altitude pregnancies, establishing an altitude-specific framework for fetal cardiac assessment. This prospective dual-group study enrolled 234 high-altitude and 252 low-altitude singleton pregnancies in Yunnan, China. Standardized Doppler ultrasound was performed at 20–25, 30–34, and 37–40 weeks. Fetal TI and hemodynamic parameters (umbilical artery [UA], ductus venosus [DV], middle cerebral artery [MCA], uterine artery [UtA]) were measured using a Samsung WS80A ultrasound system with strict angle control (<20° for vessels, <15° for TI). TI elevation: High-altitude TI was consistently higher (all p<0.001): 20–25 w: 0.471 ± 0.027 vs. 0.405 ± 0.131 (Δ16.3 %); 30–34 w: 0.492 ± 0.050 vs. 0.384 ± 0.121 (Δ28.1 %); 37–40 w: 0.484 ± 0.052 vs. 0.365 ± 0.148 (Δ32.6 %). Gestational divergence: TI decreased with gestation in high-altitude group (F=4.037, p=0.019) but remained stable in low-altitude group (F=1.421, p=0.244). TI was negatively correlated with dominant TI-MCA-PSV (r=−0.383) and TI-DV-PAV (r=−0.314) at high altitude, while showing a positive correlation with Strongest TI-UA-S/D (r=0.257) at low altitude. Chronic hypoxia induces a distinct fetal cardiovascular phenotype characterized by Tei index elevation (>0.48 post-30w), venous compromise (DV-PAV), and cerebral compensation (MCA-PSV). The tri-parametric model (TI + DV-PAV + MCA-PSV) addresses critical gaps in altitude-agnostic guidelines, offering tailored surveillance for 140 million high-altitude pregnancies globally. pubtype: Academic Journal doctype: diagnostic images research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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