Differentiation and risk stratification for gastrointestinal stromal tumors with endoscopic images using deep learning.

Purpose: Deep learning may be helpful to differentiate gastrointestinal stromal tumors and risk stratification using endoscopic images. Methods: A total of 494 patients with gastrointestinal stromal tumors and 1010 patients with gastric cancer from author's hospital were trained and validated. Anoth...

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Publicado en:Health & Technology Vol. 16; no. 5; pp. 845 - 856
Autores principales: Zheng, Qiao, Guo, Wenhao, Li, Sunjun, Zhang, Long, Sun, Jiayue, Cui, Jiaye, Jin, Xiance, Sun, Zhen
Formato: pictorial research tables/charts Journal Article
Publicado: Springer Nature Sep2026
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Sep2026
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      pub: Springer Nature
      place: New York, New York
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        10.1007/s12553-026-01088-5
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        atl: Differentiation and risk stratification for gastrointestinal stromal tumors with endoscopic images using deep learning.
      aug:
        au:
          Zheng, Qiao
          Guo, Wenhao
          Li, Sunjun
          Zhang, Long
          Sun, Jiayue
          Cui, Jiaye
          Jin, Xiance
          Sun, Zhen
        affil: https://ror.org/00rd5t069 Department of Radiation and Medical Oncology, Wenzhou Medical University First Affiliated Hospital, 325000, Wenzhou, China
      sug:
        subj:
          Gastrointestinal Neoplasms Diagnosis
          Gastrointestinal Neoplasms Risk Factors
          Neoplasms, Connective Tissue Diagnosis
          Neoplasms, Connective Tissue Risk Factors
          Deep Learning
          Diagnosis, Computer Assisted
          Endoscopy, Gastrointestinal
          Image Processing, Computer Assisted
          Diagnosis, Differential
          Risk Assessment
          Prediction Models
          Human
          Funding Source
          Cancer Patients
          Surgical Patients
          Gastrointestinal Neoplasms Surgery
          Hospitals
          Retrospective Design
          Record Review
          Data Analysis Software
          Descriptive Statistics
          T-Tests
          Chi Square Test
          Mann-Whitney U Test
          Comparative Studies
          ROC Curve
          Random Sample
          Adenocarcinoma
          Validation Studies
          Preoperative Care
          Multicenter Studies
          Gastrointestinal Neoplasms Pathology
          Neoplasms, Connective Tissue Pathology
          Biopsy
          Sensitivity and Specificity Evaluation
      ab: Purpose: Deep learning may be helpful to differentiate gastrointestinal stromal tumors and risk stratification using endoscopic images. Methods: A total of 494 patients with gastrointestinal stromal tumors and 1010 patients with gastric cancer from author's hospital were trained and validated. Another 99 patients with gastrointestinal stromal tumors and 100 patients with gastric cancer from second hospital were enrolled as external validation. Two deep learning networks, Swin Transformer and ConvNeXt were adapted for the differentiation, tumor size, mitotic index and risk stratification prediction with image level, patient level and combined level. Results: In the internal validation dataset, ConvNeXt achieved area under curve of 0.985 in the differentiation gastrointestinal stromal tumors from gastric cancer. Swin Transformer achieved a best area under curve of 0.927, 0.806 and 0.765 in the prediction of tumor size, mitotic index and risk stratification for gastrointestinal stromal tumors, respectively. In the external validation dataset, ConvNeXt achieved a best area under curve of 0.999 in the differentiation gastrointestinal stromal tumors from gastric cancer. Swin Transformer achieved a best area under curve of 0.872, 0.856 and 0.693 in the prediction of tumor size, mitotic index and risk stratification for gastrointestinal stromal tumors. Conclusions: Endoscopic images-based deep learning models demonstrated excellent performance in the differentiation gastrointestinal stromal tumors from gastric cancer, and in the prediction the tumor size, mitotic index and risk stratification of gastrointestinal stromal tumors. They are promising in the differentiation and risk stratification to improve the management of gastrointestinal stromal tumors.
      pubtype: Academic Journal
      doctype:
        pictorial
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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