First-line biologic and targeted synthetic DMARDs versus methotrexate in early rheumatoid arthritis: a meta-analysis of remission outcomes.

ObjectivesTo evaluate initial therapy with biologic and targeted synthetic DMARDs (b/tsDMARDs), compared with methotrexate, in patients with early RA.MethodsWe systematically reviewed and meta-analysed randomised-controlled trials comparing initial b/tsDMARDs, combined with methotrexate or as monoth...

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Bibliographic Details

Published in:	Rheumatology pp. 1 - 25
Main Authors:	Russell, Mark D, Chan, Chun J, Sasitharan, Aran, Allen, Victoria, Gibson, Mark, Adas, Maryam A, Goodliffe, Samantha, Bechman, Katie, Cope, Andrew P, Norton, Sam, Bosworth, Ailsa, Foxton, Peter, Price, Elizabeth, Sharrack, Sana, Dass, Shouvik, Emery, Paul, Kay, Lesley, Lanyon, Peter, Galloway, James B
Format:	Journal Article
Published:	Oxford University Press / USA Sep2026
Online Access:	View this record in EBSCOhost