Microgram-Scale Testing of Reaction Conditions in Solution Using Nanoliter Plugs in Microfluidics with Detection by MALDI-MS.
The article presents a description of a microfluidic system that is used to screen and optimize organic reaction condition on a submicrogram scale. The system uses discrete droplets as microreactors separated and transported by a continuous phase of a fluorinated carrier fluid. The system consisted...
| Publicado en: | Journal of the American Chemical Society Vol. 128; no. 8; pp. 2518 - 2520 |
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| Autores principales: | , , |
| Formato: | Artículo |
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American Chemical Society
3/1/2006
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=hlh&AN=20300064&site=ehost-live header: @attributes: shortDbName: hlh uiTerm: 20300064 longDbName: Humanities International Complete uiTag: AN controlInfo: bkinfo: jinfo: jid: 00027863 ACS jtl: Journal of the American Chemical Society issn: 00027863 maglogo: N pubinfo: dt: 3/1/2006 vid: 128 iid: 8 pid: 997 pub: American Chemical Society artinfo: ui: 20300064 10.1021/ja057720w ppf: 2518 ppct: 2 formats: tig: atl: Microgram-Scale Testing of Reaction Conditions in Solution Using Nanoliter Plugs in Microfluidics with Detection by MALDI-MS. aug: au: Hatakeyama, Takuji Chen, Delai L. Ismagilov, Rustem F. affil: Department of Chemistry, The University of Chicago, 5735 South Ellis Avenue, Chicago, Illinois 60637 su: Microfluidics Organic compounds Carbon compounds Organic chemistry Fluid dynamics Bioorganic chemistry sug: subj: Microfluidics Organic compounds Carbon compounds Organic chemistry Fluid dynamics Bioorganic chemistry ab: The article presents a description of a microfluidic system that is used to screen and optimize organic reaction condition on a submicrogram scale. The system uses discrete droplets as microreactors separated and transported by a continuous phase of a fluorinated carrier fluid. The system consisted of three components which include cartridge or reagent plugs, a PEEK Tee, and a receiving tubing. The study found a strong correlation between the fraction of peak area of the compounds. pubtype: Academic Journal doctype: Article src: R language: English refInfo: copyright: @attributes: flag: Y dt: @attributes: year: 2006 holdings: @attributes: islocal: N |
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