Theoretical Investigation of Enolborane Addition to α-Heteroatom-Substituted Aldehydes. Relevance of the Cornforth and Polar Felkin-Anh Models for Asymmetric Induction.
The addition of enolborane nucleophiles to chiral α-heteroatom-substituted aldehydes (CHCH-(X)CHO, X = F, Cl, OMe, SMe, NMe, and PMe) was investigated using density functional theory by means of B3LYP/6-31G(d) calculations, with particular emphasis on determining the relevance of the polar Felkin-An...
| Publicado en: | Journal of the American Chemical Society Vol. 128; no. 9; pp. 2920 - 2931 |
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| Autores principales: | , , |
| Formato: | Artículo |
| Publicado: |
American Chemical Society
3/8/2006
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| Materias: | |
| Acceso en línea: | Ver este registro en EBSCOhost |