Developmental Neurobiology of Bipolar Disorder and Substance Use Disorder.

The article focuses on the developmental neurobiology of bipolar disorder and its role in predicting risk for future bipolar and substance use disorders. The brain development of an adolescent which can be disrupted by both disorders involves the pruning of neurons, effect of hormones and the matura...

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Detalles Bibliográficos
Publicado en:Psychiatric Times Vol. 23; no. 9; pp. 24 - 26
Autor principal: Simkin, Deborah R.
Formato: Artículo
Publicado: MJH Life Sciences Aug2006
Materias:
Acceso en línea:Ver este registro en EBSCOhost
Descripción
Sumario:The article focuses on the developmental neurobiology of bipolar disorder and its role in predicting risk for future bipolar and substance use disorders. The brain development of an adolescent which can be disrupted by both disorders involves the pruning of neurons, effect of hormones and the maturation of the prefrontal cortex. Substance abuse increases the release of dopamine and D2 receptors. Family history is one of the risk factors of both disorders.