With 'Genes' Like That, Who Needs an Environment? Postgenomics's Argument for the 'Ontogeny of Information.'.
The linear sequence specification of a gene product is not provided by the target DNA sequence alone but by the mechanisms of gene expressions. The main actors of these mechanisms, proteins and functional RNAs, relay environmental information to the genome with important consequences to sequence sel...
| Publicado en: | Philosophy of Science Vol. 73; no. 5; pp. 905 - 918 |
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| Formato: | Artículo |
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Cambridge University Press
Dec2006
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=hlh&AN=27159522&site=ehost-live header: @attributes: shortDbName: hlh uiTerm: 27159522 longDbName: Humanities International Complete uiTag: AN controlInfo: bkinfo: jinfo: jid: 00318248 PSC jtl: Philosophy of Science issn: 00318248 maglogo: N pubinfo: dt: Dec2006 vid: 73 iid: 5 pid: 15979 pub: Cambridge University Press artinfo: ui: 27159522 10.1086/518748 ppf: 905 ppct: 13 formats: fmt: @attributes: type: P size: 785KB tig: atl: With 'Genes' Like That, Who Needs an Environment? Postgenomics's Argument for the 'Ontogeny of Information.'. aug: au: Stotz, Karola affil: Cognitive Science Program, Indiana University, 819 Eigenmann, Bloomington, IN 4740 su: Gene expression Genes Nucleotide sequence Phenotypes Epigenesis Ontogeny sug: subj: Gene expression Genes Nucleotide sequence Phenotypes Epigenesis Ontogeny ab: The linear sequence specification of a gene product is not provided by the target DNA sequence alone but by the mechanisms of gene expressions. The main actors of these mechanisms, proteins and functional RNAs, relay environmental information to the genome with important consequences to sequence selection and processing. This 'postgenomic' reality has implications for our understandings of development not as predetermined by genes but as an epigenetic process. Critics of genetic determinism have long argued that the activity of 'genes' and hence their contribution to the phenotype depends on intra- and extraorganismal 'environmental' elements. As will be shown here, even the mere physical existence of a 'gene' is dependent on its phenotypic context. pubtype: Academic Journal doctype: Article src: R language: English refInfo: copyright: @attributes: flag: Y custom: Copyright of Philosophy of Science is the property of Cambridge University Press and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. item: Philosophy of Science holder: Cambridge University Press dt: @attributes: year: 2006 holdings: @attributes: islocal: N |
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