Indanocine, a microtubule-binding indanone and a selective inducer of apoptosis in multidrug-resistant cancer cells.

Background: Certain antimitotic drugs have antitumor activities that apparently result from interactions with nontubulin components involved in cell growth and/or apoptotic cell death. Indanocine is a synthetic indanone that has been identified by the National Cancer Institute's Developmental Therap...

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Publicado en:JNCI: Journal of the National Cancer Institute Vol. 92; no. 3; pp. 217 - 225
Autores principales: Leoni, Lorenzo M., Hamel, Ernest, Genini, Davide, Shih, Hsiencheng, Carrera, Carlos J., Cottam, Howard B., Carson, Dennis A., Leoni, L M, Hamel, E, Genini, D, Shih, H, Carrera, C J, Cottam, H B, Carson, D A
Formato: research Journal Article
Publicado: Oxford University Press / USA 02/02/2000
Acceso en línea:Ver este registro en EBSCOhost