RNA, the Epicenter of Genetic Information

The origin story and emergence of molecular biology is muddled. The early triumphs in bacterial genetics and the complexity of animal and plant genomes complicate an intricate history. This book documents the many advances, as well as the prejudices and founder fallacies. It highlights the premature...

Descripción completa

Detalles Bibliográficos
Autores principales: John Mattick, Paulo Amaral
Formato: Libro
Publicado: CRC Press 2023
Materias:
Acceso en línea:Ver este registro en EBSCOhost
fields @attributes:
  recordID: 1
pdfLink:
plink: https://search.ebscohost.com/login.aspx?direct=true&db=nlebk&AN=3321891&site=ehost-live
header:
  @attributes:
    shortDbName: nlebk
    uiTerm: 3321891
    longDbName: eBook Collection (EBSCOhost)
    uiTag: AN
  controlInfo:
    bkinfo:
      btl: RNA, the Epicenter of Genetic Information
      aug:
        au:
          John Mattick
          Paulo Amaral
      isbn:
        9780367567781
        9780367623920
        9781000623086
        9781000623116
        9781003109242
    imageinfo:
    pubinfo:
      dt:
        @attributes:
          year: 2023
          month: 01
          day: 01
      dtAvail:
        @attributes:
          year: 2022
          month: 09
          day: 09
      ed: First edition
      pub: CRC Press
      pubContract: CRC Press (Unlimited)
      place: Boca Raton
      price: 0.01
      limitsGroup:
        maxCheckoutDays: 1500
        copyPages: -1
        pda: N
        printPagesOffline: 60
        printPagesOnline: 60
        previewPages: 10000
      prePubGroup:
        dewey:
          @attributes:
            class: 572.8
            item: 572 .8
        lc:
          @attributes:
            class: QH506
            item: QH 506
    artinfo:
      ui:
        3321891
        1295618543
      formats:
        fmt:
          – @attributes:
              type: EB
              doid: NL$3321891$PDF
              caption: PDF
              download: Y
          – @attributes:
              type: EK
              doid: NL$3321891$EPUB
              caption: EPUB
              download: Y
      tig:
        atl: RNA, the Epicenter of Genetic Information
        ptl: RNA, the Epicenter of Genetic Information
      aug:
        au:
          John Mattick
          Paulo Amaral
      su:
        RNA
        Molecular biology--History
        Genomes
      sug:
        subj:
          SCIENCE / Life Sciences / Molecular Biology
          SCIENCE / Life Sciences / Genetics & Genomics
          SCIENCE / History
          RNA
          Molecular biology--History
          Genomes
      ab: The origin story and emergence of molecular biology is muddled. The early triumphs in bacterial genetics and the complexity of animal and plant genomes complicate an intricate history. This book documents the many advances, as well as the prejudices and founder fallacies. It highlights the premature relegation of RNA to simply an intermediate between gene and protein, the underestimation of the amount of information required to program the development of multicellular organisms, and the dawning realization that RNA is the cornerstone of cell biology, development, brain function and probably evolution itself. Key personalities, their hubris as well as prescient predictions are richly illustrated with quotes, archival material, photographs, diagrams and references to bring the people, ideas and discoveries to life, from the conceptual cradles of molecular biology to the current revolution in the understanding of genetic information.Key Features Documents the confused early history of DNA, RNA and proteins - a transformative history of molecular biology like no other. Integrates the influences of biochemistry and genetics on the landscape of molecular biology. Chronicles the important discoveries, preconceptions and misconceptions that retarded or misdirected progress. Highlights major pioneers and contributors to molecular biology, with a focus on RNA and noncoding DNA. Summarizes the mounting evidence for the central roles of non-protein-coding RNA in cell and developmental biology. Provides a thought-provoking retrospective and forward-looking perspective for advanced students and professional researchers. The Open Access version of this book, available at www.taylorfrancis.com, has been made available under a Creative Commons Attribution-Non Commercial-No Derivatives 4.0 license.
      pubtype: eBook
      doctype: Book
      ougenre: Book
    language: English
    copyright:
      @attributes:
        flag: N
      copyrightText:
    holdings:
      @attributes:
        islocal: N