A Dramatic Switch of Enantioselectivity in Asymmetric Heck Reaction by Benzylic Substituents of Ligands.

A series of benzylic substituted P,N-ligands 1 and 2 have been synthesized. The Pd-complexes of these ligands show high catalytic activity and enantioselectivity in catalyzing the asymmetric Heck reaction. A dramatic switch in enantioselectivity is realized using ligands with and without substituent...

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Bibliographic Details

Published in:	Journal of the American Chemical Society Vol. 130; no. 30; pp. 9717 - 9726
Main Authors:	Wen-Qiong Wu, Qian Peng, Da-Xuan Dong, Xue-long Hou, Yun-Dong Wu
Format:	Article
Published:	American Chemical Society 7/30/2008
Subjects:	Ligands (Chemistry) Organic synthesis Palladium Transition metal complexes Density functionals Reaction mechanisms (Chemistry)
Online Access:	View this record in EBSCOhost