Disseminated cryptococcosis in an AIDS patient with unusual clinical presentation.

Disseminated cryptocococcosis is a rare and often fatal disease. Here in we report an unusual fatal case of disseminated cryptococcosis. The patient presented with a past history of postmenopausal bleeding with loss of consciousness, altered mental status, few seizures and a low grade fever. Lumbar...

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Publicado en:Revista Iberoamericana de Micologia Vol. 25; no. 3; pp. 179 - 182
Autores principales: Basu, Somansu, Jain, Puneet, Ansari, Sajid, Al-Arimi, Sumaya Salem, Singh, S. K.
Formato: Artículo
Publicado: Elsevier B.V. sep2008
Materias:
Acceso en línea:Ver este registro en EBSCOhost
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        atl: Disseminated cryptococcosis in an AIDS patient with unusual clinical presentation.
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          Basu, Somansu
          Jain, Puneet
          Ansari, Sajid
          Al-Arimi, Sumaya Salem
          Singh, S. K.
        affil:
          Department of Microbiology, Sur Hospital, Ministry of Health, Oman
          Department of Pathology, Sur Hospital, Ministry of Health, Oman
          Department of Medicine, Sur Hospital, Ministry of Health, Oman
      su:
        Cryptococcosis
        AIDS patients
        Cryptococcus neoformans
        Anti-infective agents
        Vaginitis
      sug:
        subj:
          Cryptococcosis
          AIDS patients
          Cryptococcus neoformans
          Anti-infective agents
          Vaginitis
      keyword:
        AIDS
        Disseminated cryptococcosis
        Criptococosis diseminada
        Sida
        Vaginitis
      ab:
        Disseminated cryptocococcosis is a rare and often fatal disease. Here in we report an unusual fatal case of disseminated cryptococcosis. The patient presented with a past history of postmenopausal bleeding with loss of consciousness, altered mental status, few seizures and a low grade fever. Lumbar puncture revealed elevated pressure, lymphocytic pleocytosis, elevated protein and markedly reduced glucose level. Cryptococcus neoformans was isolated from cerebrospinal fluid and blood. Serological assay revealed the presence of human immunodeficiency virus. The patient was treated with antifungal agents intravenously without any signs of improvement and the patient passed away after two weeks of therapy. This is the first case report of disseminated cryptococcosis in an AIDS patient suffering from cryptoccoccal vaginitis.
        La criptococosis diseminada es una enfermedad poco común y, a menudo, fatal. Los autores presentan el caso de una mujer con esta enfermedad. El historial de la paciente incluía sangrado posmenopáusico, pérdida del conocimiento, alteración de la conciencia, ataques y febrícula. La punción lumbar reveló presión alta del líquido cefalorraquídeo, pleocitosis linfocitaria, tasas elevadas de proteínas y bajos niveles de glucosa. Cryptococcus neoformans fue aislado en líquido cefalorraquídeo y sangre. Un análisis serológico reveló la presencia del virus de la inmunodeficiencia humana. La paciente fue tratada con agentes antimicóticos por vía intravenosa, sin observarse mejoría, y falleció tras dos semanas de tratamiento. Este es el primer caso de criptococosis diseminada en una paciente con sida y vaginitis criptocócica.
      pubtype: Academic Journal
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    language: English
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