Simple and Generalized Synthesis of Oxide—Metal Heterostructured Nanoparticles and their Applications in Multimodal Biomedical Probes.

Heterostructured nanoparticles composed of metals and FeO or MnO were synthesized by thermal decomposition of mixtures of metal-oleate complexes (for the oxide component) and metal-oleylamine complexes (for the metal component). The products included flowerlike-shaped nanoparticles of Pt-FeO and Ni-...

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Published in:Journal of the American Chemical Society Vol. 130; no. 46; pp. 15573 - 15581
Main Authors: Sang-Hyun Choi, Hyon Bin Na, Yong II Park, Kwangjin An, Soon Gu Kwon, Youngjin Jang, Mi-hyun Park, Jaewon Moon, Jae Sung Son, In Chan Song, Woo Kyung Moon, Taeghwan Hyeon
Format: Article
Published: American Chemical Society 11/19/2008
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Online Access:View this record in EBSCOhost
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      dt: 11/19/2008
      vid: 130
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      pub: American Chemical Society
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        35398162
        10.1021/ja805311x
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        atl: Simple and Generalized Synthesis of Oxide—Metal Heterostructured Nanoparticles and their Applications in Multimodal Biomedical Probes.
      aug:
        au:
          Sang-Hyun Choi
          Hyon Bin Na
          Yong II Park
          Kwangjin An
          Soon Gu Kwon
          Youngjin Jang
          Mi-hyun Park
          Jaewon Moon
          Jae Sung Son
          In Chan Song
          Woo Kyung Moon
          Taeghwan Hyeon
        affil:
          National Creative Research Initiative Center for Oxide Nanocrystalline Materials and School of Chemical and Biological Engineering, Seoul National Universily, Seoul 151-744, Korea
          Department of Radiology, Seoul National University College of Medicine, Seoul National University Hospital, Seoul /10-744, Korea
      su:
        Nanoparticles
        Oxides
        Inorganic synthesis
        Heterostructures
        Electronic probes
        X-ray diffraction
        Oligonucleotides
      sug:
        subj:
          Nanoparticles
          Oxides
          Inorganic synthesis
          Heterostructures
          Electronic probes
          X-ray diffraction
          Oligonucleotides
      ab: Heterostructured nanoparticles composed of metals and FeO or MnO were synthesized by thermal decomposition of mixtures of metal-oleate complexes (for the oxide component) and metal-oleylamine complexes (for the metal component). The products included flowerlike-shaped nanoparticles of Pt-FeO and Ni-FeO and snowmanlike-shaped nanoparticles of Ag-MnO and Au-MnO. Powder X-ray diffraction patterns showed that these nanoparticles were composed of face-centered cubic (fcc)-structured FeO or MnO and fcc-structured metals. The relaxivity values of the Au-MnO and Au-FeO nanoparticles were similar to those of the MnO and FeO nanoparticles, respectively. Au-FeO heterostructured narioparticles conjugated with two kinds of 12-base oligonucleotide sequences were able to sense a complementary 24-mer sequence, causing nanoparticle aggregation. This hybridization-mediated aggregation was detected by the overall size increase indicated by dynamic light scattering data, the red shift of the surface plasmon band of the Au component, and the enhancement of the signal intensity of the FeO component in T-weighted magnetic resonance imaging.
      pubtype: Academic Journal
      doctype: Article
      src: R
    language: English
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          year: 2008
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