Toward a Chemical Mechanism of Proton Pumping by the B-Type Cytochrome c Oxidases: Application of Density Functional Theory to Cytochrome ba[sub3] of Thermus thermophilus.

A mechanism for proton pumping by the B-type cytochrome c oxidases is presented in which one proton is pumped in conjunction with the weakly exergonic, two-electron reduction of Fe-bound O[sub2] to the Fe-Cu bridging peroxodianion and three protons are pumped in conjunction with the highly exergonic...

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Publicado en:	Journal of the American Chemical Society Vol. 130; no. 45; pp. 15002 - 15022
Autores principales:	Fee, James A., Case, David A., Noodleman, Louis
Formato:	Artículo
Publicado:	American Chemical Society 11/12/2008
Materias:	Protons Cytochrome c Oxidases Density functionals Enzyme activation Chemical reduction Imidazoles Electrons Bilayer lipid membranes
Acceso en línea:	Ver este registro en EBSCOhost