Molecular identification and susceptibility testing of Trichosporon isolates from a Brazilian hospital.
In this study the molecular identification and susceptibility profile of 21 clinical isolates, from a Brazilian hospital, belonging to six different species of Trichosporon were described. Trichosporon asahii was the predominant species and corresponded to 43% of isolates followed by Trichosporon fa...
| Publicado en: | Revista Iberoamericana de Micologia Vol. 25; no. 4; pp. 221 - 226 |
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| Autores principales: | , , , , |
| Formato: | Artículo |
| Publicado: |
Elsevier B.V.
dic2008
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| Materias: | |
| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=lth&AN=36491092&site=ehost-live header: @attributes: shortDbName: lth uiTerm: 36491092 longDbName: MedicLatina uiTag: AN controlInfo: bkinfo: jinfo: jid: 11301406 PVP jtl: Revista Iberoamericana de Micologia issn: 11301406 maglogo: N pubinfo: dt: dic2008 vid: 25 iid: 4 pid: 467 pub: Elsevier B.V. artinfo: ui: 36491092 ppf: 221 ppct: 5 formats: fmt: @attributes: type: P size: 546KB tig: atl: Molecular identification and susceptibility testing of Trichosporon isolates from a Brazilian hospital. aug: au: Ribeiro, Mariceli Araujo Alastruey-Izquierdo, Ana Gomez-Lopez, Alicia Rodriguez-Tudela, Juan Luis Cuenca-Estrella, Manuel affil: Nucleo de Doenças Infecciosas, Universidade Federal do Espirito Santo, Brazil Servicio de Micología, Centro Nacional de Microbiología, Istituto de Salud Carlos III, Majadahonda, Madrid, Spain su: Yeast Microbial sensitivity tests Amphotericin B Effect of antibiotics on microorganisms Drug resistance in microorganisms sug: subj: Yeast Microbial sensitivity tests Amphotericin B Effect of antibiotics on microorganisms Drug resistance in microorganisms keyword: Antifungal susceptibility Molecular identification Trichosporon asahii Trichosporon inkin Identificación molecular Sensibilidad a los antifúngicos Trichosporon asahii Trichosporon inkin ab: In this study the molecular identification and susceptibility profile of 21 clinical isolates, from a Brazilian hospital, belonging to six different species of Trichosporon were described. Trichosporon asahii was the predominant species and corresponded to 43% of isolates followed by Trichosporon faecale (24%) and Trichosporon inkin (14%). Eighty three percent of the strains isolated from deep sites were identified as T. asahii, while only 17% belong to a non-T, asahii species (Trichosporon inkin). In general, the MICs were high and independent of the species of Trichosporon as well as the clinical origin of strain. Amphotericin B, 5-fluorocytosine and fluconazole were the less active against Trichosporon spp. and high MIC values of voriconazole, posaconazole and ravuconazole were observed. Fifty-six percent (5/9) of T. asahii strains were isolated from deep sites, whereas 8% (1/12) of non-T, asahii strains were isolated from those sites. A total of 89% of T. asahii isolates exhibited resistance to amphotericin B in vitro. En este artículo se describe la identificación molecular y el perfil de sensibilidad de 21 cepas clínicas pertenecientes a seis especies diferentes del género Trichosporon. La especie predominante fue Trichosporon asahii, que supuso el 43% de los aislamientos, seguido de Trichosporon faecale (24%) y Trichosporon inkin (14%). El 83% de las cepas aisladas de lugares anatómicos profundos fueron identificadas como T. asahii, mientras que sólo un 17% pertenecian a especies no-T, asahii. En general, los valores de CMI fueron altos, independientemente de la especie de Trichosporon y el origen clínico de la cepa. Los antifúngicos menos activos frente a Trichosporon fueron anfotericina B, fluorocitosina y fluconazol, aunque también se observaron valores altos de CMI a voriconazol, posaconazol y ravuconazol. El cincuenta y seis por ciento (5/9) de las cepas de T. asahii fueron aisladas de muestras profundas, mientas que el 8% (1/12) de las especies no-T, asahii fueron aisladas de dichos lugares. El 89% de los aislamientos de T. asahii mostraron resistencia in vitro a la anfotericina B. pubtype: Academic Journal doctype: Article src: R language: English refInfo: copyright: @attributes: flag: Y custom: Copyright of Revista Iberoamericana de Micologia is the property of Elsevier B.V. and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. item: Revista Iberoamericana de Micologia holder: Elsevier B.V. dt: @attributes: year: 2008 holdings: @attributes: islocal: N |
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