Phthalocyanine Dimerization-Based Molecular Beacons Using Near-IR Fluorescence.

The article presents a study that developed a double-labeled dimerization-based molecular beacons (DBMB) which integrate the phthalocyanines (Pc's) of near-infrared (IR) fluorophores. It states that the DBMB creates efficient quenching and signal-to-background (SB) ratio and can be used in live cell...

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Detalles Bibliográficos
Publicado en:	Journal of the American Chemical Society Vol. 131; no. 7; pp. 2432 - 2434
Autores principales:	Nesterova, Irina V., Erdem, S. Sibel, Pakhomov, Serhii, Hammer, Robert P., Soper, Steven A.
Formato:	Artículo
Publicado:	American Chemical Society 2/25/2009
Materias:	Molecular beams Infrared spectroscopy Photon scattering Phthalocyanines Matrices (Mathematics) Imaging systems
Acceso en línea:	Ver este registro en EBSCOhost

Descripción
Sumario:	The article presents a study that developed a double-labeled dimerization-based molecular beacons (DBMB) which integrate the phthalocyanines (Pc's) of near-infrared (IR) fluorophores. It states that the DBMB creates efficient quenching and signal-to-background (SB) ratio and can be used in live cell imaging or other applications that require monitoring of biological matrices. It relates that the doubling of the extinction coefficient and fluorescent photon is the notable feature of the design.