Manipulating Crystal Orientation in Nanoscale Cylindrical Pores by Stereochemical Inhibition.

Glycine nanocrystals, grown in aligned nanometer-scale cylindrical pores of nanoporous polystyrene-poly(dimethyl acrylamide) monoliths by evaporation of imbibed aqueous solutions, adopt preferred orientations with their fast-growth axes aligned parallel with the pore direction. X-ray diffraction ana...

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Publicado en:Journal of the American Chemical Society Vol. 131; no. 7; pp. 2588 - 2597
Autores principales: Hamilton, Benjamin D., Weissbuch, Isabelle, Lahav, Meir, HiIlmyer, Marc A., Ward, Michael D.
Formato: Artículo
Publicado: American Chemical Society 2/25/2009
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Acceso en línea:Ver este registro en EBSCOhost
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      dt: 2/25/2009
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      pub: American Chemical Society
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        10.1021/ja807193s
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        atl: Manipulating Crystal Orientation in Nanoscale Cylindrical Pores by Stereochemical Inhibition.
      aug:
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          Hamilton, Benjamin D.
          Weissbuch, Isabelle
          Lahav, Meir
          HiIlmyer, Marc A.
          Ward, Michael D.
        affil:
          Department of Chemical Engineering and Materials Science, University of Minnesota, Minneapolis, Minnesota 55455
          Department of Materials and Interfaces, Weizmann Institute of Science, 76100 Rehovot, Israel
          Department of Chemistry, University of Minnesota, Minneapolis, Minnesota 55455
          Molecular Design Institute, Department of Chemistry, New York University, 100 Washington Square East, New York, New York 10003-6688
      su:
        Glycine
        Nanocrystals
        Axes
        Crystallization
        Enantiomers
        Optical diffraction
      sug:
        subj:
          Glycine
          Nanocrystals
          Axes
          Crystallization
          Enantiomers
          Optical diffraction
      ab: Glycine nanocrystals, grown in aligned nanometer-scale cylindrical pores of nanoporous polystyrene-poly(dimethyl acrylamide) monoliths by evaporation of imbibed aqueous solutions, adopt preferred orientations with their fast-growth axes aligned parallel with the pore direction. X-ray diffraction analysis revealed the exclusive formation of the metastable β-polymorph, with crystal size comparable with the 22 nm pore diameter, in contrast to the formation of α-glycine in the absence of nanoscale confinement. When grown from aqueous solutions alone, the nanocrystals were oriented with their [010] and [0(...)0] axes, the native fast growth directions of the (+) and (-) enantiomorphs of β-glycine, respectively, aligned parallel with the pore direction. In contrast, crystallization in the presence of racemic mixtures of chiral auxiliaries known to inhibit growth along the [010] and [0(...)0] directions of the enantiomorphs produced β-glycine nanocrystals with their [001] axes nearly parallel to the pore direction. Enantiopure auxiliaries that inhibit crystallization along the native fast growth direction of only one of the enantiomorphs allow the other enantiomorph to grow with the [010] axis parallel to the cylinder. Collectively, these results demonstrate that crystal growth occurs such that the fast-growing direction, which can be altered by adding chiral auxiliaries, is parallel to the pore direction. This behavior can be attributed to a competition between differently aligned crystals due to critical size effects, the minimization of the surface energy of specific crystal planes, and a more effective reduction of the excess free energy associated with supersaturated conditions when the crystal grows with its fast-growth axis unimpeded by pore walls. These observations suggest that the β-glycine nanocrystals form by homogeneous nucleation, with minimal influence of the pore walls on orientation.
      pubtype: Academic Journal
      doctype: Article
      src: R
    language: English
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          year: 2009
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