The Role of Causal Processes in the Neutral and Nearly Neutral Theories.

The neutral and nearly neutral theories of molecular evolution are sometimes characterized as theories about drift alone, where drift is described solely as an outcome, rather than a process. We argue, however, that both selection and drift, as causal processes, are integral parts of both theories....

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Publicado en:Philosophy of Science Vol. 75; no. 5; pp. 548 - 560
Autores principales: Dietrich, Michael R., Millstein, Roberta L.
Formato: Artículo
Publicado: Cambridge University Press Dec2008
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Acceso en línea:Ver este registro en EBSCOhost
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          Dietrich, Michael R.
          Millstein, Roberta L.
        affil:
          Department of Biological Sciences, Dartmouth College, Hanover, NH 03755
          Department of Philosophy, University of California, Davis, One Shields Avenue, Davis, CA 95616
      su:
        Molecular evolution
        Origin of life
        Molecular biology
        Philosophy of science
        Philosophy & science
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        subj:
          Molecular evolution
          Origin of life
          Molecular biology
          Philosophy of science
          Philosophy & science
      ab: The neutral and nearly neutral theories of molecular evolution are sometimes characterized as theories about drift alone, where drift is described solely as an outcome, rather than a process. We argue, however, that both selection and drift, as causal processes, are integral parts of both theories. However, the nearly neutral theory explicitly recognizes alleles and/or molecular substitutions that, while engaging in weakly selected causal processes, exhibit outcomes thought to be characteristic of random drift. A narrow focus on outcomes obscures the significant role of weakly selected causal processes in the nearly neutral theory.
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