Antimicrobials, Antibiotic Resistance, Antibiofilm Strategies and Activity Methods

To prevent bacterial adherence, invasion and infection, antimicrobials such as antibiotics are being used and vastly researched nowdays. Several factors such as natural selection, mutations in genes, the presence of efflux pumps, impermeability of the cell wall, structural changes in enzymes and rec...

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Detalles Bibliográficos
Autor principal: Sahra Kırmusaoğlu
Formato: Libro
Publicado: IntechOpen 2019
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Acceso en línea:Ver este registro en EBSCOhost
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        atl: Antimicrobials, Antibiotic Resistance, Antibiofilm Strategies and Activity Methods
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        au: Sahra Kırmusaoğlu
      su:
        Antibiotics--Physiological effect
        Anti-infective agents
        Drug resistance
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          MEDICAL / Microbiology
          Antibiotics--Physiological effect
          Anti-infective agents
          Drug resistance
      ab: To prevent bacterial adherence, invasion and infection, antimicrobials such as antibiotics are being used and vastly researched nowdays. Several factors such as natural selection, mutations in genes, the presence of efflux pumps, impermeability of the cell wall, structural changes in enzymes and receptors, biofilm formation, and quorum sensing cause microorganisms to develop resistance against antimicrobials. Isolates that synthesize extended spectrum-β-lactamases (ESBL), induced β-lactamases (IBL), carbapenamases, metallo-β-lactamases (MBLs), and New Delhi metallo-β-lactamases (NDM) have emerged. Determining virulence factors such as biofilms and the level of antimicrobial activities of antimicrobial agents alone and in combination with appropriate doses against microorganisms is very important for the diagnosis, inhibition, and prevention of microbial infection. The goal of this book is to provide information on all these topics.
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