Catalysis via Homolytic Substitutions with C-O and Ti-O Bonds: Oxidative Additions and Reductive Eliminations in Single Electron Steps.

In a combined theoretical and experimental study, an efficient catalytic reaction featuring epoxide opening and tetrahydrofuran formation through homolytic substitution reactions at C-O and Ti-O bonds was devised. The performance of these two key steps of the catalytic cycle was studied and could be...

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Publicado en:Journal of the American Chemical Society Vol. 131; no. 46; pp. 16989 - 17000
Autores principales: Gansäuer, Andreas, Fleckhaus, André, Lafont, Manue Alejandre, Okkel, Andreas, Kotsis, Konstantinos, Anoop, Anakuthil, Neese, Frank
Formato: Artículo
Publicado: American Chemical Society 11/25/2009
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Acceso en línea:Ver este registro en EBSCOhost
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        atl: Catalysis via Homolytic Substitutions with C-O and Ti-O Bonds: Oxidative Additions and Reductive Eliminations in Single Electron Steps.
      aug:
        au:
          Gansäuer, Andreas
          Fleckhaus, André
          Lafont, Manue Alejandre
          Okkel, Andreas
          Kotsis, Konstantinos
          Anoop, Anakuthil
          Neese, Frank
        affil:
          Kekulé-Institut für Organische Chemie und Biochemie der Uniuersitat Bonn, Gerhard Domagk Str. 1, 53121 Bonn, Germany
          Institut für Physikalische und Theoretische Chemie der Universitar Bonn, Wegeler Str. 12, 53115 Bonn, Germany
      su:
        Catalysis
        Chemical bonds
        Epoxy compounds
        Tetrahydrofuran
        Oxidation-reduction reaction
        Electrons
      sug:
        subj:
          Catalysis
          Chemical bonds
          Epoxy compounds
          Tetrahydrofuran
          Oxidation-reduction reaction
          Electrons
      ab: In a combined theoretical and experimental study, an efficient catalytic reaction featuring epoxide opening and tetrahydrofuran formation through homolytic substitution reactions at C-O and Ti-O bonds was devised. The performance of these two key steps of the catalytic cycle was studied and could be adjusted by modifying the electronic properties of the catalysts through introduction of electron-donating or -withdrawing substituents to the titanocene catalysts. By regarding both steps as single electron versions of oxidative addition and reductive elimination, a mechanism-based platform for the design of catalysts and reagents for electron transfer reactions evolved that opens broad perspectives for further investigations.
      pubtype: Academic Journal
      doctype: Article
      src: R
    language: English
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