Practical Guide to genetic association studies. Considerations on their clinical usefulness.

The article offers information on the useful guidelines in conducting research related to genetics. Several variables should be considered to measure the sample size including genotyping errors, statistical tests and size of expected effect. An examination of the population mix is required to assess...

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Detalles Bibliográficos
Publicado en:	Nefrología Vol. 29; no. 6; pp. 582 - 589
Autores principales:	Esparragón, F. Rodríguez, Pérez, J. C. Rodríguez, García^Bello, M. A.
Formato:	Artículo
Publicado:	Revista Nefrologia Dec2009
Materias:	Genetic research Research methodology Sample size (Statistics) Genotype-environment interaction Population Heterogeneity Quantitative research Logistic regression analysis
Acceso en línea:	Ver este registro en EBSCOhost

Descripción
Sumario:	The article offers information on the useful guidelines in conducting research related to genetics. Several variables should be considered to measure the sample size including genotyping errors, statistical tests and size of expected effect. An examination of the population mix is required to assess genetic heterogeneity. The type of statistical analysis applied should also be regarded including contingency analysis, logistic regression and coefficient interpretation.