Recyclization Rate of a Photocleaved Peptide from Multiscale Simulation.

The article presents a study which examines the conformational changes that multiscale simulation can bring to the recyclization rate and dynamics of photocleaved peptide. It states that the study validated the energy surface of the peptide based from the density functional theory (DFT). It mentions...

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Publicado en:Journal of the American Chemical Society Vol. 132; no. 6; pp. 1778 - 1780
Autores principales: Nieber, Harald, Hellweg, Arnim, Dottsinis, Nikos L.
Formato: Artículo
Publicado: American Chemical Society 2/17/2010
Materias:
Acceso en línea:Ver este registro en EBSCOhost
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      dt: 2/17/2010
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        atl: Recyclization Rate of a Photocleaved Peptide from Multiscale Simulation.
      aug:
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          Nieber, Harald
          Hellweg, Arnim
          Dottsinis, Nikos L.
        affil:
          Lehrstuhl für Theoretische Chemie, Ruhr- Universität Bochum, 44780 Bochum, Germany
          Department of Physics, King's College London, London WC2R 2LS, United Kingdom
      su:
        Protein folding
        Molecular dynamics
        Density functionals
        Polypeptides
        Potential energy surfaces
        Recombinant proteins
      sug:
        subj:
          Protein folding
          Molecular dynamics
          Density functionals
          Polypeptides
          Potential energy surfaces
          Recombinant proteins
      ab: The article presents a study which examines the conformational changes that multiscale simulation can bring to the recyclization rate and dynamics of photocleaved peptide. It states that the study validated the energy surface of the peptide based from the density functional theory (DFT). It mentions that classical molecular dynamics (CMD) simulation was used to assess the recombination of photocleavage. It concludes that condensed phase triggers the blockage of photocleavage in protein folding.
      pubtype: Academic Journal
      doctype: Article
      src: R
    language: English
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