Unilateral renal agenesis: case review of ambulatory pediatric nephrology clinics in Cali.

Introduction: Unilateral renal agenesis is a frequent renal malformation with incidence of 1 per 1000 live born children. There are no statistics nor protocols to manage and follow-up these patients. Usually asymptomatic, it can be early detected by prenatal ultrasound, allowing opportune detection...

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Publicado en:Colombia Medica Vol. 41; no. 1; pp. 41.52 - 49.52
Autores principales: DE ROVETTO, CONSUELO RESTREPO, URCUQUI, LUZ ÁNGELA, VALENCIA, MARIBEL, DE CASTAÑO, IRIS, MARTÍNEZ, ALEXANDER MAXIMILIANO
Formato: Artículo
Publicado: Universidad del Valle ene-mar2010
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Acceso en línea:Ver este registro en EBSCOhost
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        atl: Unilateral renal agenesis: case review of ambulatory pediatric nephrology clinics in Cali.
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          DE ROVETTO, CONSUELO RESTREPO
          URCUQUI, LUZ ÁNGELA
          VALENCIA, MARIBEL
          DE CASTAÑO, IRIS
          MARTÍNEZ, ALEXANDER MAXIMILIANO
        affil:
          Professor and Chief of Department of Pediatrics, School of Medicine, Universidad del Valle, Cali, Colombia.
          Pediatrics resident, Department of Pediatrics, School of Medicine, Universidad del Valle, Cali, Colombia.
          Associate Professor, Department of Pediatrics, School of Medicine, Universidad del Valle, Cali, Colombia.
          Epidemiology Master’s candidate, School of Public Health, Universidad del Valle, Cali, Colombia.
      su:
        Kidney abnormalities
        Pediatrics
        Prenatal diagnosis
        Urinary tract infections
        Longitudinal method
        Diagnosis
        Patients
      sug:
        subj:
          Kidney abnormalities
          Pediatrics
          Prenatal diagnosis
          Urinary tract infections
          Longitudinal method
          Diagnosis
          Patients
      keyword:
        Body-mass index
        Hydronephrosis
        Proteinuria
        Renal insufficiency
        Unilateral renal agenesis
        Vesicoureteral reflux
        Índice masa corporal
        Agenesia renal unilateral
        Diagnóstico prenatal
        Hidronefrosis
        Infecciones del tracto urinario
        Insuficiencia renal
        Proteinuria
        Reflujo vésico-ureteral
      ab:
        Introduction: Unilateral renal agenesis is a frequent renal malformation with incidence of 1 per 1000 live born children. There are no statistics nor protocols to manage and follow-up these patients. Usually asymptomatic, it can be early detected by prenatal ultrasound, allowing opportune detection and adequate follow up. The goal is to describe main features found in children with renal agenesis at four ambulatory pediatric nephrology clinics in Cali, Colombia: Hospital Universitario del Valle (HUV), Club Noel Children's hospital and the private practice of two pediatric nephrologists. Methods: This is a retrospective descriptive study in a series of cases with congenital renal agenesis diagnosed between January, 1995 and December 2007, of patients under 18 years of age and based on a review of clinical records. Results: 43 patients were found, 51.2% males, 88% from the department of Valle del Cauca. Prenatal diagnoses were conducted in only 21% of these patients; agenesis was right in 48.8% and left in 51.2%. In 46.5%, association with other pathologies was found: occult spinal bifida, congenital scoliosis, and Klippel-Feil sequence. Compensatory renal hypertrophy was reported in 39.5% of the patients, 42% had episodes of urinary tract infection, 31% vesicoureteral reflux and 10% proteinuria. Four male patients (9.3%) developed renal failure. The average follow-up was 6.6 years. Conclusions: Prenatal diagnose was not very frequent in our set of cases. Urinary tract infection and vesicoureteral reflux were common, increasing the risk of renal deterioration. Prolonged follow up is suggested, with unified protocols to prevent renal failure.
        Introducción: La agenesia renal unilateral (ARU) es una malformación con una incidencia de 1 por 1000 nacidos vivos. En Colombia no hay estadísticas ni protocolos para el manejo y seguimiento de estos pacientes. La ARU casi siempre es asintomática y se puede descubrir temprano por ecografía prenatal, que permite el adecuado seguimiento. El objetivo es describir las características principales encontradas en la revisión de historias clínicas de niños con agenesia renal que se examinaron en dos servicios de nefrología pediátrica de la ciudad de Cali: Hospital Universitario del Valle (HUV), Hospital Infantil Club Noel (HICN) y en los consultorios de dos nefrólogas pediatras. Metodología: Es un estudio descriptivo retrospectivo de tipo serie de casos basado en la revisión de historias clínicas, de pacientes menores de 18 años con diagnóstico de agenesia renal congénita atendidos entre enero de 1995 y diciembre de 2007. Resultados: Se encontraron 43 pacientes, 51.2% masculinos. El 88% procedía del departamento del Valle. El diagnóstico prenatal sólo se hizo en 21% de los casos. En 48.8% de los pacientes la agenesia renal fue derecha y en el resto izquierda. En 46.5% hubo asociación con otras entidades (espina bífida oculta, escoliosis congénita y secuencia de Klippel Feil). En 39.5% de los pacientes se vio hipertrofia renal compensatoria, 42% presentaron algún episodio de infección urinaria, 31% reflujo vésico-ureteral y 10% proteinuria; en 4 pacientes (9.3%), todos varones desarrollaron falla renal. El promedio de seguimiento fue 6.6 años. Conclusiones: El diagnóstico prenatal fue poco frecuente en esta serie de casos. La infección urinaria y el reflujo vésicoureteral son altos y aumentan el riesgo de daños renales. Se recomienda el seguimiento extendido en niños con ARU, mediante protocolos unificados para prevenir el deterioro renal.
      pubtype: Academic Journal
      doctype: Article
      src: R
    language: English
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