Indoor air pollution from biomass combustion and acute respiratory infections in Kenya: an exposure-response study.
Background: Acute respiratory infections (ARI) are the leading cause of the global burden of disease and have been causally linked with exposure to pollutants from domestic biomass fuels in less-developed countries. We used longitudinal health data coupled with detailed monitoring of personal exposu...
| Publicado en: | Lancet Vol. 358; no. 9282; pp. 619 - 625 |
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| Autores principales: | , , , |
| Formato: | research Journal Article |
| Publicado: |
Lancet
8/25/2001
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=5054112&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 5054112 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 01406736 LAN jtl: Lancet issn: 01406736 maglogo: N pubinfo: dt: 8/25/2001 vid: 358 iid: 9282 pid: 1297 pub: Lancet place: Philadelphia, Pennsylvania artinfo: ui: 5054112 5054112 NLM11530148 5054112 10.1016/S0140-6736(01)05777-4 NLM11530148 5054112 ppf: 619 ppct: 6 formats: fmt: – @attributes: type: T – @attributes: type: C – @attributes: type: P tig: atl: Indoor air pollution from biomass combustion and acute respiratory infections in Kenya: an exposure-response study. aug: au: Ezzati, Majid Kammen, Daniel M Ezzati, M Kammen, D affil: Center for Risk Management, Resources for the Future, Washington, DC, USA sug: subj: Environmental Monitoring Methods Air Pollutants Analysis Air Pollution, Indoor Analysis Respiratory Tract Infections Etiology Models, Statistical Infant Energy-Generating Resources Adolescence Human Epidemiology Heating Developing Countries Female Air Pollutants Adverse Effects Infant, Newborn Air Pollution, Indoor Acute Disease Child Kenya Air Pollution, Indoor Adverse Effects Ecosystem Public Health Adult Logistic Regression Regression Housing Respiratory Tract Infections Epidemiology Child, Preschool Cooking Middle Age Male Validation Studies Comparative Studies Evaluation Research Multicenter Studies Personal Resource Questionnaire Scales Infant: 1-23 months Adolescent: 13-18 years Infant, Newborn: birth-1 month Child: 6-12 years Adult: 19-44 years Child, Preschool: 2-5 years Middle Aged: 45-64 years Female Male ab: Background: Acute respiratory infections (ARI) are the leading cause of the global burden of disease and have been causally linked with exposure to pollutants from domestic biomass fuels in less-developed countries. We used longitudinal health data coupled with detailed monitoring of personal exposure from more than 2 years of field measurements in rural Kenya to estimate the exposure-response relation for particulates smaller than 10 mm in diameter (PM(10)) generated from biomass combustion.Methods: 55 randomly-selected households (including 93 infants and children, 229 individuals between 5 and 49 years of age, and 23 aged 50 or older) in central Kenya were followed up for more than 2 years. Longitudinal data on ARI and acute lower respiratory infections (ALRI) were recorded at weekly clinical examinations. Exposure to PM(10) was monitored by measurement of PM(10) emission concentration and time-activity budgets.Findings: With the best estimate of the exposure-response relation, we found that ARI and ALRI are increasing concave functions of average daily exposure to PM(10), with the rate of increase declining for exposures above about 1000-2000 mg/m(3). After we had included high-intensity exposure episodes, sex was no longer a significant predictor of ARI and ALRI.Interpretation: The benefits of reduced exposure to PM(10) are larger for average exposure less than about 1000-2000 mg/m(3). Our findings have important consequences for international public-health policies, energy and combustion research, and technology transfer efforts that affect more than 2 billion people worldwide. pubtype: Academic Journal doctype: research Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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