Excitotoxic lesions of the hippocampus leave sensory preconditioning intact: implications for models of hippocampal function.
Learning about contextual cues is markedly disrupted in rats with hippocampal lesions. One analysis of this disruption is that it reflects a general failure to form associations between the elements of complex events. A straightforward prediction of this analysis is that sensory preconditioning wi...
| Publicado en: | Behavioral Neuroscience Vol. 115; no. 6; pp. 1357 - 1363 |
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| Autores principales: | , , |
| Formato: | Artículo |
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American Psychological Association
December 2001
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ssf&AN=506238082&site=ehost-live header: @attributes: shortDbName: ssf uiTerm: 506238082 longDbName: Social Sciences Full Text (H.W. Wilson) uiTag: AN controlInfo: bkinfo: jinfo: jid: 07357044 BEN jtl: Behavioral Neuroscience issn: 07357044 maglogo: N pubinfo: dt: December 2001 vid: 115 iid: 6 pid: 34 pub: American Psychological Association artinfo: ui: 506238082 10.1037/0735-7044.115.6.1357 ppf: 1357 ppct: 6 formats: tig: atl: Excitotoxic lesions of the hippocampus leave sensory preconditioning intact: implications for models of hippocampal function. aug: au: Ward-Robinson, Jasper Coutureau, Etienne Good, Mark su: Laboratory rats Hippocampus (Brain) Conditioned response Brain function localization sug: subj: Laboratory rats Hippocampus (Brain) Conditioned response Brain function localization ab: Learning about contextual cues is markedly disrupted in rats with hippocampal lesions. One analysis of this disruption is that it reflects a general failure to form associations between the elements of complex events. A straightforward prediction of this analysis is that sensory preconditioning will be disrupted by hippocampal lesions. This prediction was assessed by presenting rats with flavored solutions composed of 2 elements (A and X) before X was paired with an injection of the emetic, lithium chloride. A subsequent test revealed that rats were less willing to consume Solution A than they were to consume a control solution, B. This was true of rats with sham lesions and those with excitotoxic lesions of hippocampus. These findings fail to support the proposition that the hippocampus-dependent deficit in contextual conditioning is due to a general disruption to the process of associating the elements of complex events. Reprinted by permission of the publisher. pubtype: Academic Journal doctype: Article src: R language: English refInfo: copyright: @attributes: flag: N holdings: @attributes: islocal: N |
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