Fear conditioning and brain activity: a positron emission tomography study in humans.
Regional cerebral blood flow (rCBF) was measured with H215O positron emission tomography in 8 healthy women before and after fear conditioning (i.e. paired shocks) and unpaired shocks to videotape cues. Conditioning was supported by enhanced peripheral nervous system recordings and subjective ratin...
| Publicado en: | Behavioral Neuroscience Vol. 114; no. 4; pp. 671 - 681 |
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| Autores principales: | , , |
| Formato: | Artículo |
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American Psychological Association
August 2000
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ssf&AN=506264105&site=ehost-live header: @attributes: shortDbName: ssf uiTerm: 506264105 longDbName: Social Sciences Full Text (H.W. Wilson) uiTag: AN controlInfo: bkinfo: jinfo: jid: 07357044 BEN jtl: Behavioral Neuroscience issn: 07357044 maglogo: N pubinfo: dt: August 2000 vid: 114 iid: 4 pid: 34 pub: American Psychological Association artinfo: ui: 506264105 10.1037/0735-7044.114.4.671 ppf: 671 ppct: 10 formats: tig: atl: Fear conditioning and brain activity: a positron emission tomography study in humans. aug: au: Fischer, H. Andersson, J. L. R. Furmark, T. su: Emotional conditioning Fear Brain function localization Cerebellum sug: subj: Emotional conditioning Fear Brain function localization Cerebellum ab: Regional cerebral blood flow (rCBF) was measured with H215O positron emission tomography in 8 healthy women before and after fear conditioning (i.e. paired shocks) and unpaired shocks to videotape cues. Conditioning was supported by enhanced peripheral nervous system recordings and subjective ratings. Fear conditioning increased rCBF in the central gray of the midbrain; bilaterally in the hippothalamus, the thalamus, and the left striatum; and in the right and left anterior cingulate and right prefrontal cortices. Regional CBF was attenuated bilaterally in the right and left prefrontal, temporal (including the amygdala), parietal, and ocipital cortices, and in the left orbitofrontal cortex. When compared with unpaired shock presentations, fear conditioning resulted in elevated rCBF in the left cerebellum. Hence, in the present paradigm, only neural activity in the left cerebellum solely reflected processes associated with true Pavlovian conditioning. Reprinted by permission of the publisher. pubtype: Academic Journal doctype: Article src: R language: English refInfo: copyright: @attributes: flag: N holdings: @attributes: islocal: N |
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