Olfactory Learning and Memory Impairments Following Lesions to the Hippocampus and Perirhinal-Entorhinal Cortex.
The role of the hippocampus and perirhinal-entorhinal cortex was examined in an olfactory discrimination paradigm. Small neurotoxic lesions of the hippocampus (21% tissue damage) yielded relatively unimpaired olfactory retention across brief (30 s), intermediate (approximately 5 min), and 24-hr dela...
| Publicado en: | Behavioral Neuroscience Vol. 117; no. 2; pp. 304 - 320 |
|---|---|
| Autores principales: | , , |
| Formato: | Artículo |
| Publicado: |
American Psychological Association
April 2003
|
| Materias: | |
| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ssf&AN=506416143&site=ehost-live header: @attributes: shortDbName: ssf uiTerm: 506416143 longDbName: Social Sciences Full Text (H.W. Wilson) uiTag: AN controlInfo: bkinfo: jinfo: jid: 07357044 BEN jtl: Behavioral Neuroscience issn: 07357044 maglogo: N pubinfo: dt: April 2003 vid: 117 iid: 2 pid: 34 pub: American Psychological Association artinfo: ui: 506416143 10.1037/0735-7044.117.2.304 ppf: 304 ppct: 16 formats: tig: atl: Olfactory Learning and Memory Impairments Following Lesions to the Hippocampus and Perirhinal-Entorhinal Cortex. aug: au: Kant, Kevin P. Bunsey, Michael D. Riccio, David C. su: Brain function localization Laboratory rats Discrimination learning Animal memory sug: subj: Brain function localization Laboratory rats Discrimination learning Animal memory ab: The role of the hippocampus and perirhinal-entorhinal cortex was examined in an olfactory discrimination paradigm. Small neurotoxic lesions of the hippocampus (21% tissue damage) yielded relatively unimpaired olfactory retention across brief (30 s), intermediate (approximately 5 min), and 24-hr delays, whereas impairments were noted at 5-day retention intervals. Larger hippocampal lesions (63% tissue damage) spared memory at intermediate delays, with no impact at 8-day retention intervals. Aspiration lesions directed at the perirhinal-entorhinal cortex produced a variable performance pattern, with impairments noted at intermediate, 24-hr, and 5-day delays. Results suggest the hippocampus is not specifically involved in retaining olfactory information, with additional consideration given to the relationship between lesion size and memory impairment. Reprinted by permission of the publisher. pubtype: Academic Journal doctype: Article src: R language: English refInfo: copyright: @attributes: flag: N holdings: @attributes: islocal: N |
|---|