Visceral Afferent Bias on Cortical Processing: Role of Adrenergic Afferents to the Basal Forebrain Cholinergic System.
Intraperitoneal epinephrine enhances the cerebral auditory evoked potential (AEP), an effect that is dependent on the basal forebrain cortical cholinergic system. The present study examined the hypothesis that ascending noradrenergic projections from brainstem autonomic substrates to the basal foreb...
| Publicado en: | Behavioral Neuroscience Vol. 118; no. 6; pp. 1455 - 1460 |
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| Autores principales: | , , |
| Formato: | Artículo |
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American Psychological Association
December 2004
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ssf&AN=506522491&site=ehost-live header: @attributes: shortDbName: ssf uiTerm: 506522491 longDbName: Social Sciences Full Text (H.W. Wilson) uiTag: AN controlInfo: bkinfo: jinfo: jid: 07357044 BEN jtl: Behavioral Neuroscience issn: 07357044 maglogo: N pubinfo: dt: December 2004 vid: 118 iid: 6 pid: 34 pub: American Psychological Association artinfo: ui: 506522491 10.1037/0735-7044.118.6.1455 ppf: 1455 ppct: 5 formats: tig: atl: Visceral Afferent Bias on Cortical Processing: Role of Adrenergic Afferents to the Basal Forebrain Cholinergic System. aug: au: Knox, Dayan Sarter, Martin Berntson, Gary C. su: Brain function localization Auditory evoked response Adrenaline Laboratory rats sug: subj: Brain function localization Auditory evoked response Adrenaline Laboratory rats keyword: Epinephrine ab: Intraperitoneal epinephrine enhances the cerebral auditory evoked potential (AEP), an effect that is dependent on the basal forebrain cortical cholinergic system. The present study examined the hypothesis that ascending noradrenergic projections from brainstem autonomic substrates to the basal forebrain cholinergic system represent an essential component of the ascending pathway mediating this effect of epinephrine. Epinephrine again enhanced the AEP in rats, and this effect was attenuated by infusion of the selective α1 adrenergic antagonist terazosin into the basal forebrain. Moreover, infusions of the selective α1 adrenergic agonist phenylephrine into the basal forebrain mimicked the priming effects of epinephrine. Results support the hypothesis that noradrenergic afferents to the basal forebrain cholinergic system represent a component of an ascending visceral afferent system. Reprinted by permission of the publisher. pubtype: Academic Journal doctype: Article src: R language: English refInfo: copyright: @attributes: flag: N holdings: @attributes: islocal: N |
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