Dopamine D1 and D2 Receptor Antagonism in the Preoptic Area Produces Different Effects on Maternal Behavior in Lactating Rats.
The preoptic area (POA) is critical for maternal behavior in rats but little is known about what neurotransmitters released here influence maternal responding. POA infusion of 10 μg (but not 2 μg) of the dopamine D1 receptor antagonist SCH-23390 greatly impaired retrieval and licking of pups but not...
| Publicado en: | Behavioral Neuroscience Vol. 119; no. 4; pp. 1072 - 1084 |
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| Autores principales: | , |
| Formato: | Artículo |
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American Psychological Association
August 2005
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ssf&AN=506621714&site=ehost-live header: @attributes: shortDbName: ssf uiTerm: 506621714 longDbName: Social Sciences Full Text (H.W. Wilson) uiTag: AN controlInfo: bkinfo: jinfo: jid: 07357044 BEN jtl: Behavioral Neuroscience issn: 07357044 maglogo: N pubinfo: dt: August 2005 vid: 119 iid: 4 pid: 34 pub: American Psychological Association artinfo: ui: 506621714 10.1037/0735-7044.119.4.1072 ppf: 1072 ppct: 12 formats: tig: atl: Dopamine D1 and D2 Receptor Antagonism in the Preoptic Area Produces Different Effects on Maternal Behavior in Lactating Rats. aug: au: Miller, Stephanie M. Lonstein, Joseph S. su: Laboratory rats Parental behavior in animals Dopamine -- Receptors Brain function localization sug: subj: Laboratory rats Parental behavior in animals Dopamine -- Receptors Brain function localization ab: The preoptic area (POA) is critical for maternal behavior in rats but little is known about what neurotransmitters released here influence maternal responding. POA infusion of 10 μg (but not 2 μg) of the dopamine D1 receptor antagonist SCH-23390 greatly impaired retrieval and licking of pups but not other maternal or nonmaternal behaviors in lactating rats. In contrast, POA infusion of 10 μg (but not 2 μg) of the D2 receptor antagonist raclopride facilitated nursing but did not affect oral maternal behaviors. SCH-23390 in the medial hypothalamus tended to impair licking but not retrieval. Raclopride in the medial hypothalamus had no effects. Therefore, D1 and D2 receptor activity, particularly in the POA, is important for regulating different maternal behaviors. Reprinted by permission of the publisher. pubtype: Academic Journal doctype: Article src: R language: English refInfo: copyright: @attributes: flag: N holdings: @attributes: islocal: N |
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