The Bed Nucleus of the Stria Terminalis Is Critically Involved in Enhancing Associative Learning After Stressful Experience.

Exposure to an acute stressful event enhances trace eyeblink conditioning in male rats, even when rats begin training days after the stressor (Shors, 2001). The authors examined whether the bed nucleus of the stria terminalis (BNST), an area involved in stress and anxiety, is critically involved in...

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Published in:Behavioral Neuroscience Vol. 119; no. 6; pp. 1459 - 1467
Main Authors: Bangasser, Debra A., Santollo, Jessica, Shors, Tracey J.
Format: Article
Published: American Psychological Association December 2005
Subjects:
Online Access:View this record in EBSCOhost
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      dt: December 2005
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        10.1037/0735-7044.119.6.1459
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        atl: The Bed Nucleus of the Stria Terminalis Is Critically Involved in Enhancing Associative Learning After Stressful Experience.
      aug:
        au:
          Bangasser, Debra A.
          Santollo, Jessica
          Shors, Tracey J.
      su:
        Psychology of learning
        Association of ideas
        Laboratory rats
        Brain function localization
      sug:
        subj:
          Psychology of learning
          Association of ideas
          Laboratory rats
          Brain function localization
      keyword: Association (Psychology)
      ab: Exposure to an acute stressful event enhances trace eyeblink conditioning in male rats, even when rats begin training days after the stressor (Shors, 2001). The authors examined whether the bed nucleus of the stria terminalis (BNST), an area involved in stress and anxiety, is critically involved in this effect and, if so, when. The authors found that excitotoxic lesions to the BNST prevented the enhanced conditioning after stressor exposure. In addition, temporary inactivation of the BNST during the stressor did not alter enhanced responding, whereas inactivation during training prevented the enhancement. These data indicate that stressful experience induces persistent changes in the BNST that are necessary for enhancing learning well after the stressful event has ceased. Reprinted by permission of the publisher.
      pubtype: Academic Journal
      doctype: Article
      src: R
    language: English
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