The Impact of Selective Amygdala, Orbital Frontal Cortex, or Hippocampal Formation Lesions on Established Social Relationships in Rhesus Monkeys (Macaca mulatta)

Social dominance, personality ratings, and frequency, duration, and timing of social behaviors were measured pre- and postsurgically in 6 groups of rhesus monkeys (Macaca mulatta), each consisting of 1 sham-operated control and 1 monkey each with a selective amygdala, hippocampal, or orbital frontal...

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Publicado en:Behavioral Neuroscience Vol. 120; no. 4; pp. 761 - 787
Autores principales: Machado, Christopher J., Bachevalier, Jocelyne
Formato: Artículo
Publicado: American Psychological Association August 2006
Materias:
Acceso en línea:Ver este registro en EBSCOhost
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      pub: American Psychological Association
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        atl: The Impact of Selective Amygdala, Orbital Frontal Cortex, or Hippocampal Formation Lesions on Established Social Relationships in Rhesus Monkeys (Macaca mulatta)
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        au:
          Machado, Christopher J.
          Bachevalier, Jocelyne
      su:
        Brain function localization
        Laboratory monkeys
        Social dominance
        Personality
        Social behavior in mammals
        Primates
      sug:
        subj:
          Brain function localization
          Laboratory monkeys
          Social dominance
          Personality
          Social behavior in mammals
          Primates
      ab: Social dominance, personality ratings, and frequency, duration, and timing of social behaviors were measured pre- and postsurgically in 6 groups of rhesus monkeys (Macaca mulatta), each consisting of 1 sham-operated control and 1 monkey each with a selective amygdala, hippocampal, or orbital frontal cortex lesion. Unlike previous reports, none of the operated groups showed changes in social dominance postsurgery, although changes in other measures varied by lesion site. Although sham-operated monkeys displayed heightened avoidant, anxious, and aggressive behaviors, those with hippocampal lesions also showed increased exploration and excitability, along with reduced responses to affiliative signals. Amygdala lesions yielded several personality changes that precluded positive social interactions (increased exploration and excitability, decreased affiliation and popularity) and altered responses to threatening social signals. By contrast, monkeys with orbital frontal lesions were involved in more aggressive interactions and responded differently to both affiliative and threatening signals. Although several findings differ from earlier nonhuman primate studies, they are largely in agreement with human data and emphasize the context-specific nature of social behavior studies. Interpretation of results in relation to cognitive processes mediated by each structure is discussed. Reprinted by permission of the publisher.
      pubtype: Academic Journal
      doctype: Article
      src: R
    language: English
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