Neural Dynamics Underlying Impaired Autonomic and Conditioned Responses Following Amygdala and Orbitofrontal Lesions.
A neural model is presented that explains how outcome-specific learning modulates affect, decisionmaking, and Pavlovian conditioned approach responses. The model addresses how brain regions responsible for affective learning and habit learning interact and answers a central question: What are the re...
| Publicado en: | Behavioral Neuroscience Vol. 122; no. 5; pp. 1100 - 1126 |
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| Autores principales: | , , |
| Formato: | Artículo |
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American Psychological Association
October 2008
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ssf&AN=506848127&site=ehost-live header: @attributes: shortDbName: ssf uiTerm: 506848127 longDbName: Social Sciences Full Text (H.W. Wilson) uiTag: AN controlInfo: bkinfo: jinfo: jid: 07357044 BEN jtl: Behavioral Neuroscience issn: 07357044 maglogo: N pubinfo: dt: October 2008 vid: 122 iid: 5 pid: 34 pub: American Psychological Association artinfo: ui: 506848127 10.1037/a0012808 ppf: 1100 ppct: 26 formats: tig: atl: Neural Dynamics Underlying Impaired Autonomic and Conditioned Responses Following Amygdala and Orbitofrontal Lesions. aug: au: Grossberg, Stephen Bullock, Daniel Dranias, Mark R. su: Brain function localization Computer simulation Amygdaloid body Cerebral cortex sug: subj: Brain function localization Computer simulation Amygdaloid body Cerebral cortex ab: A neural model is presented that explains how outcome-specific learning modulates affect, decisionmaking, and Pavlovian conditioned approach responses. The model addresses how brain regions responsible for affective learning and habit learning interact and answers a central question: What are the relative contributions of the amygdala and orbitofrontal cortex to emotion and behavior? In the model, the amygdala calculates outcome value while the orbitofrontal cortex influences attention and conditioned responding by assigning value information to stimuli. Model simulations replicate autonomic, electrophysiological, and behavioral data associated with three tasks commonly used to assay these phenomena: Food consumption, Pavlovian conditioning, and visual discrimination. Interactions of the basal ganglia and amygdala with sensory and orbitofrontal cortices enable the model to replicate the complex pattern of spared and impaired behavioral and emotional capacities seen following lesions of the amygdala and orbitofrontal cortex. Reprinted by permission of the publisher. pubtype: Academic Journal doctype: Article src: R language: English refInfo: copyright: @attributes: flag: N holdings: @attributes: islocal: N |
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