Deficits in Landmark Navigation and Path Integration After Lesions of the Interpeduncular Nucleus.

Experiments were designed to determine the role of the interpeduncular nucleus (IPN) in 3 forms of navigation: beacon, landmark, and path integration. In beacon navigation, animals reach goals using cues directly associated with them, whereas in landmark navigation animals use external cues to deter...

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Publicado en:Behavioral Neuroscience Vol. 123; no. 3; pp. 490 - 504
Autores principales: Clark, Benjamin J., Taube, Jeffrey S.
Formato: Artículo
Publicado: American Psychological Association June 2009
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Acceso en línea:Ver este registro en EBSCOhost
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      dt: June 2009
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      pub: American Psychological Association
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        atl: Deficits in Landmark Navigation and Path Integration After Lesions of the Interpeduncular Nucleus.
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          Clark, Benjamin J.
          Taube, Jeffrey S.
      su:
        Mesencephalon
        Brain function localization
        Animal navigation
        Laboratory rats
      sug:
        subj:
          Mesencephalon
          Brain function localization
          Animal navigation
          Laboratory rats
      ab: Experiments were designed to determine the role of the interpeduncular nucleus (IPN) in 3 forms of navigation: beacon, landmark, and path integration. In beacon navigation, animals reach goals using cues directly associated with them, whereas in landmark navigation animals use external cues to determine a direction and distance to goals. Path integration refers to the use of self-movement cues to obtain a trajectory to a goal. IPN-lesioned rats were tested in a food-carrying task in which they searched for food in an open field, and returned to a refuge after finding the food. Landmark navigation was evaluated during trials performed under lighted conditions and path integration was tested under darkened conditions, thus eliminating external cues. We report that IPN lesions increased the number of errors and reduced heading accuracy under both lighted and darkened conditions. Tests using a Morris water maze procedure indicated that IPN lesions produced moderate impairments in the landmark version of the water task, but left beacon navigation intact. These findings suggest that the IPN plays a fundamental role in landmark navigation and path integration. Reprinted by permission of the publisher.
      pubtype: Academic Journal
      doctype: Article
      src: R
    language: English
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