Role of a Lateralized Parietal-Basal Ganglia Circuit in Hierarchical Pattern Perception: Evidence From Parkinson's Disease.

The role of corticostriatal circuits in hierarchical pattern perception was examined in Parkinson's disease. The hypothesis was tested that patients with right-side onset of motor symptoms (RPD, left hemisphere dysfunction) would be impaired at local level processing because the left posterior tempo...

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Publicado en:Behavioral Neuroscience Vol. 123; no. 1; pp. 125 - 137
Autores principales: Schendan, Haline E., Amick, Melissa M., Cronin-Golomb, Alice
Formato: Artículo
Publicado: American Psychological Association February 2009
Materias:
Acceso en línea:Ver este registro en EBSCOhost
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        atl: Role of a Lateralized Parietal-Basal Ganglia Circuit in Hierarchical Pattern Perception: Evidence From Parkinson's Disease.
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        au:
          Schendan, Haline E.
          Amick, Melissa M.
          Cronin-Golomb, Alice
      su:
        Visual perception
        Laterality
        Cerebral hemispheres
        Functional assessment of Parkinson's disease patients
      sug:
        subj:
          Visual perception
          Laterality
          Cerebral hemispheres
          Functional assessment of Parkinson's disease patients
      ab: The role of corticostriatal circuits in hierarchical pattern perception was examined in Parkinson's disease. The hypothesis was tested that patients with right-side onset of motor symptoms (RPD, left hemisphere dysfunction) would be impaired at local level processing because the left posterior temporoparietal junction (TP) emphasizes processing of local information. By contrast, left-side onset patients (LPD; right hemisphere dysfunction) would show impaired global processing because right TP emphasizes global processing. Participants identified targets at local or global levels without and with attention biased toward those levels. Despite normal attentional control between levels, LPD patients showed a single dissociation, demonstrating abnormal global level processing under all conditions, whereas RPD patients showed abnormal local level processing mainly when attention was biased toward the local level. These findings link side of motor symptom onset to visuospatial cognitive abilities that depend upon the contralateral TP, highlighting that side of onset can predict visuospatial impairments, and provide evidence that an inferior parietal — basal ganglia pathway involving the caudate head and the hemispherically asymmetrical TP region is necessary for hierarchical pattern perception. Reprinted by permission of the publisher.
      pubtype: Academic Journal
      doctype: Article
      src: R
    language: English
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