Increased error-related negativity (ERN) in childhood anxiety disorders: ERP and source localization.
Background: In this study we used event-related potentials (ERPs) and source localization analyses to track the time course of neural activity underlying response monitoring in children diagnosed with an anxiety disorder compared to age-matched low-risk normal controls. Methods: High-density ERPs we...
| Publicado en: | Journal of Child Psychology & Psychiatry & Allied Disciplines. Vol. 47; no. 10; pp. 1073 - 1083 |
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| Autores principales: | , , |
| Formato: | Artículo |
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HWW Temp
October 2006
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ssf&AN=507918453&site=ehost-live header: @attributes: shortDbName: ssf uiTerm: 507918453 longDbName: Social Sciences Full Text (H.W. Wilson) uiTag: AN controlInfo: bkinfo: jinfo: jid: 00219630 D9TW jtl: Journal of Child Psychology & Psychiatry & Allied Disciplines. issn: 00219630 maglogo: N pubinfo: dt: October 2006 vid: 47 iid: 10 pid: 71778 pub: HWW Temp artinfo: ui: 507918453 10.1111/j.1469-7610.2006.01654.x ppf: 1073 ppct: 10 formats: tig: atl: Increased error-related negativity (ERN) in childhood anxiety disorders: ERP and source localization. aug: au: Ladouceur, Cecile D. Dahl, Ronald E. Birmaher, Boris su: Anxiety disorders Errors Brain function localization Electroencephalography Child psychology sug: subj: Anxiety disorders Errors Brain function localization Electroencephalography Child psychology keyword: Anxiety neurosis ab: Background: In this study we used event-related potentials (ERPs) and source localization analyses to track the time course of neural activity underlying response monitoring in children diagnosed with an anxiety disorder compared to age-matched low-risk normal controls. Methods: High-density ERPs were examined following errors on a flanker task from 12 children between 8 and 14 years old diagnosed with an anxiety disorder (ANX) and 13 age-matched low-risk normal controls (LRNC). Results: Children diagnosed with an anxiety disorder had increased error-related negativity (ERN) amplitude. The neural generators of the ERN in the ANX group were estimated to be localized in the anterior cingulate cortex (ACC). There were no significant group differences in PE amplitude. Conclusions: These data provide evidence for increased ERN amplitude localized to the ACC in children diagnosed with an anxiety disorder, suggesting altered maturational patterns of the ACC circuitry early in the course of this illness. Reprinted by permission of the publisher. pubtype: Periodical doctype: Article src: R language: English refInfo: copyright: @attributes: flag: N holdings: @attributes: islocal: N |
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