Campylobacter pylori detected noninvasively by the 13C-urea breath test.
The high endogenous urease activity of Campylobacter pylori was exploited in a non-invasive test for the presence of this organism in the stomach. When 13C-urea was administered orally after a test meal, urea-derived 13CO2 appeared in the respiratory CO2 of infected individuals at a constant rate fo...
| Publicado en: | Lancet Vol. 1; no. 8543; pp. 1174 - 1178 |
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| Autores principales: | , , , , , , , , , , , , , |
| Formato: | clinical trial research randomized controlled trial Journal Article |
| Publicado: |
Lancet
5/23/1987
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=5080217&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 5080217 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 01406736 LAN jtl: Lancet issn: 01406736 maglogo: N pubinfo: dt: 5/23/1987 vid: 1 iid: 8543 pid: 1297 pub: Lancet place: Philadelphia, Pennsylvania artinfo: ui: 5080217 5080217 NLM2883491 5080217 10.1016/s0140-6736(87)92145-3 NLM2883491 5080217 ppf: 1174 ppct: 4 formats: tig: atl: Campylobacter pylori detected noninvasively by the 13C-urea breath test. aug: au: Graham, David Y. Evans Jr., Doyle J. Alpert, Lesley C. Klein, Peter D. Evans, Dolores G. Opekun, Antone R. Boutton, Thomas W. Graham, D Y Klein, P D Evans, D J Jr Evans, D G Alpert, L C Opekun, A R Boutton, T W affil: Department of Medicine, USDA/ARS Children's Nutrition Research Center, Baylor College of Medicine, Houston, Texas, USA sug: subj: Campylobacter Infections Diagnosis Breath Tests Methods Urea Female Gastritis Microbiology Urease Analysis Human Middle Age Pyloric Antrum Microbiology Isotopes Adult Campylobacter Evaluation Research Male Carbon Dioxide Analysis Clinical Trials Validation Studies Comparative Studies Multicenter Studies Randomized Controlled Trials Clinical Assessment Tools Middle Aged: 45-64 years Adult: 19-44 years Female Male ab: The high endogenous urease activity of Campylobacter pylori was exploited in a non-invasive test for the presence of this organism in the stomach. When 13C-urea was administered orally after a test meal, urea-derived 13CO2 appeared in the respiratory CO2 of infected individuals at a constant rate for greater than 100 min. The test was validated in 26 individuals who underwent both the 13C-urea breath test and endoscopic biopsy of the antral mucosa for culture and histological examination. Each positive breath test proved to be correlated with a positive culture or Warthin-Starry silver stain of a mucosal biopsy specimen, or both. pubtype: Academic Journal doctype: clinical trial research randomized controlled trial Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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