Effects of Aging on the Neural Correlates of Successful Item and Source Memory Encoding.
To investigate the neural basis of age-related source memory (SM) deficits, young and older adults were scanned with fMRI while encoding faces, scenes, and face-scene pairs. Successful encoding activity was identified by comparing encoding activity for subsequently remembered versus forgotten items...
| Publicado en: | Journal of Experimental Psychology. Learning, Memory & Cognition Vol. 34; no. 4; pp. 791 - 809 |
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| Autores principales: | , , , , , |
| Formato: | Artículo |
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American Psychological Association
July 2008
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ssf&AN=508075191&site=ehost-live header: @attributes: shortDbName: ssf uiTerm: 508075191 longDbName: Social Sciences Full Text (H.W. Wilson) uiTag: AN controlInfo: bkinfo: jinfo: jid: 02787393 EXL jtl: Journal of Experimental Psychology. Learning, Memory & Cognition issn: 02787393 maglogo: N pubinfo: dt: July 2008 vid: 34 iid: 4 pid: 34 pub: American Psychological Association artinfo: ui: 508075191 10.1037/0278-7393.34.4.791 ppf: 791 ppct: 18 formats: tig: atl: Effects of Aging on the Neural Correlates of Successful Item and Source Memory Encoding. aug: au: Dennis, Nancy A. Prince, Steven E. Hayes, Scott M. Madden, David J. Huettel, Scott A. Cabeza, Roberto su: Brain function localization Autobiographical memory Age factors in memory Recollection (Psychology) sug: subj: Brain function localization Autobiographical memory Age factors in memory Recollection (Psychology) keyword: Episodic memory ab: To investigate the neural basis of age-related source memory (SM) deficits, young and older adults were scanned with fMRI while encoding faces, scenes, and face-scene pairs. Successful encoding activity was identified by comparing encoding activity for subsequently remembered versus forgotten items or pairs. Age deficits in successful encoding activity in hippocampal and prefrontal regions were more pronounced for SM (pairs) as compared with item memory (faces and scenes). Age-related reductions were also found in regions specialized in processing faces (fusiform face area) and scenes (parahippocampal place area), but these reductions were similar for item and SM. Functional connectivity between the hippocampus and the rest of the brain was also affected by aging; whereas connections with posterior cortices were weaker in older adults, connections with anterior cortices, including prefrontal regions, were stronger in older adults. Taken together, the results provide a link between SM deficits in older adults and reduced recruitment of hippocampal and prefrontal regions during encoding. The functional connectivity findings are consistent with a posterior-anterior shift with aging previously reported in several cognitive domains and linked to functional compensation. Reprinted by permission of the publisher. pubtype: Academic Journal doctype: Article src: R language: English refInfo: copyright: @attributes: flag: N holdings: @attributes: islocal: N |
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