Maximizing heritability of a linear combination of traits.

In 1971 Jones proposed an approximate procedure for finding that linear combination of scores which has maximum heritability in a twin sample. I give an exact small-sample procedure. I point out two problems: such procedures can over-optimize the heritability by capitalizing on chance, and confid...

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Publicado en:Psychological Reports Vol. 75; pp. 467 - 477
Autor principal: Grove, William M.
Formato: Artículo
Publicado: Ammons Scientific, Ltd. August 1994 pt2
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Acceso en línea:Ver este registro en EBSCOhost
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        atl: Maximizing heritability of a linear combination of traits.
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        au: Grove, William M.
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        Human genetics
        Psychological techniques
        Psychology -- Statistical methods
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          Human genetics
          Psychological techniques
          Psychology -- Statistical methods
      ab: In 1971 Jones proposed an approximate procedure for finding that linear combination of scores which has maximum heritability in a twin sample. I give an exact small-sample procedure. I point out two problems: such procedures can over-optimize the heritability by capitalizing on chance, and confidence intervals and significance tests are needed. I give an approach using James-Stein shrinkage estimation and bootstrapped standard errors to address these problems. It appears that confidence intervals may be quite broad. To reduce the width of the confidence intervals, one can accept some small-sample bias in exchange for smaller sampling errors. The James-Stein approach to estimating coefficients is used to achieve reduced confidence interval width. I illustrate with a computational example using personality data. Reprinted by permission of the publisher, 1994.
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    language: English
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