Executive Function and Cognitive Subprocesses in First-Episode, Drug-Naive Schizophrenia: An Analysis of N-Back Performance.
Objective: This study investigated changes in the cognitive architecture of N-back performance in schizophrenia. Method: N-back performance of 12 patients with first-episode, drug-naive schizophrenia and matched healthy comparison subjects was studied in a reaction-time decomposition paradigm. Resul...
| Publicado en: | American Journal of Psychiatry Vol. 162; no. 6; pp. 1206 - 1209 |
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| Autores principales: | , , |
| Formato: | Artículo |
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American Psychiatric Publishing, Inc.
June 2005
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ssf&AN=511241005&site=ehost-live header: @attributes: shortDbName: ssf uiTerm: 511241005 longDbName: Social Sciences Full Text (H.W. Wilson) uiTag: AN controlInfo: bkinfo: jinfo: jid: 0002953X API jtl: American Journal of Psychiatry issn: 0002953X maglogo: N pubinfo: dt: June 2005 vid: 162 iid: 6 pid: 37323 pub: American Psychiatric Publishing, Inc. artinfo: ui: 511241005 10.1176/appi.ajp.162.6.1206 ppf: 1206 ppct: 3 formats: tig: atl: Executive Function and Cognitive Subprocesses in First-Episode, Drug-Naive Schizophrenia: An Analysis of N-Back Performance. aug: au: Krieger, Stephan Lis, Stefanie Cetin, Turan su: Short-term memory Schizophrenia Human information processing sug: subj: Short-term memory Schizophrenia Human information processing ab: Objective: This study investigated changes in the cognitive architecture of N-back performance in schizophrenia. Method: N-back performance of 12 patients with first-episode, drug-naive schizophrenia and matched healthy comparison subjects was studied in a reaction-time decomposition paradigm. Results: Imposition of a working memory load led to a significant drop in response accuracy in patients. Reaction-time decomposition suggested slowing of visuomotor and choice reaction processing as well as an inability of parallel processing directed by working memory. Discussion: Although N-back tasks validly access working memory function as a neurocognitive trait in the illness, several additional subprocesses and the ability for cognitive parallel processing are altered and require further study in schizophrenia. Reprinted by permission of the publisher. pubtype: Academic Journal doctype: Article src: R language: English refInfo: copyright: @attributes: flag: N holdings: @attributes: islocal: N |
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