Prefrontal Brain Activity Predicts Temporally Extended Decision-Making Behavior.

Although functional neuroimaging studies of human decision-making processes are increasingly common, most of the research in this area has relied on passive tasks that generate little individual variability. Relatively little attention has been paid to the ability of brain activity to predict overt...

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Published in:Journal of the Experimental Analysis of Behavior Vol. 84; no. 3; pp. 537 - 555
Main Authors: Yarkoni, Tal, Braver, Todd S., Gray, Jeremy R.
Format: Article
Published: Society for the Experimental Analysis of Behavior November 2005
Subjects:
Online Access:View this record in EBSCOhost
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      dt: November 2005
      vid: 84
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        10.1901/jeab.2005.121-04
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        atl: Prefrontal Brain Activity Predicts Temporally Extended Decision-Making Behavior.
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        au:
          Yarkoni, Tal
          Braver, Todd S.
          Gray, Jeremy R.
      su:
        Brain function localization
        Frontal lobe
        Choice (Psychology)
      sug:
        subj:
          Brain function localization
          Frontal lobe
          Choice (Psychology)
      ab: Although functional neuroimaging studies of human decision-making processes are increasingly common, most of the research in this area has relied on passive tasks that generate little individual variability. Relatively little attention has been paid to the ability of brain activity to predict overt behavior. Using functional magnetic resonance imaging (fMRI), we investigated the neural mechanisms underlying behavior during a dynamic decision task that required subjects to select smaller, short-term monetary payoffs in order to receive larger, long-term gains. The number of trials over which the long-term gains accrued was manipulated experimentally (2 versus 12). Event-related neural activity in right lateral prefrontal cortex, a region associated with high-level cognitive processing, selectively predicted choice behavior in both conditions, whereas insular cortex responded to fluctuations in amount of reward but did not predict choice behavior. These results demonstrate the utility of a functional neuroimaging approach in behavioral psychology, showing that (a) highly circumscribed brain regions are capable of predicting complex choice behavior, and (b) fMRI has the ability to dissociate the contributions of different neural mechanisms to particular behavioral tasks. Reprinted by permission of the publisher.
      pubtype: Academic Journal
      doctype: Article
      src: R
    language: English
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