Alterations in the functional anatomy of working memory in adult attention deficit hyperactivity disorder.
|WbObjective:[|WB] The authors used a functional neuroimaging study with a working memory probe to investigate the pathophysiology of attention deficit hyperactivity disorder (ADHD). Their goal was to compare regional cerebral blood flow (rCBF) changes related to working memory in adults with and...
| Publicado en: | American Journal of Psychiatry Vol. 157; no. 2; pp. 278 - 281 |
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| Autores principales: | , , |
| Formato: | Artículo |
| Publicado: |
American Psychiatric Publishing, Inc.
February 2000
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| Materias: | |
| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ssf&AN=512937412&site=ehost-live header: @attributes: shortDbName: ssf uiTerm: 512937412 longDbName: Social Sciences Full Text (H.W. Wilson) uiTag: AN controlInfo: bkinfo: jinfo: jid: 0002953X API jtl: American Journal of Psychiatry issn: 0002953X maglogo: N pubinfo: dt: February 2000 vid: 157 iid: 2 pid: 37323 pub: American Psychiatric Publishing, Inc. artinfo: ui: 512937412 10.1176/appi.ajp.157.2.278 ppf: 278 ppct: 3 formats: tig: atl: Alterations in the functional anatomy of working memory in adult attention deficit hyperactivity disorder. aug: au: Schweitzer, Julie B. Faber, Tracy L. Grafton, Scott T. su: Adults Attention-deficit hyperactivity disorder Regional blood flow Brain function localization Short-term memory sug: subj: Adults Attention-deficit hyperactivity disorder Regional blood flow Brain function localization Short-term memory ab: |WbObjective:[|WB] The authors used a functional neuroimaging study with a working memory probe to investigate the pathophysiology of attention deficit hyperactivity disorder (ADHD). Their goal was to compare regional cerebral blood flow (rCBF) changes related to working memory in adults with and without ADHD. |WbMethod:[|WB] Using {15O}H2O positron emission tomography (PET) studies, the authors compared the sites of neural activation related to working memory in six adult men diagnosed with ADHD and six healthy men without ADHD who were matched in age and general intelligence. |WbResults:[|WB] Task-related changes in rCBF in the men without ADHD were more prominent in the frontal and temporal regions, but rCBF changes in men with ADHD were more widespread and primarily located in the occipital regions. |WbConclusions:[|WB] These data suggest the use of compensatory mental and neural strategies by subjects with ADHD in response to a disrupted ability to inhibit attention to non relevant stimuli and the use of internalized speech to guide behavior. Reprinted by permission of the publisher. pubtype: Academic Journal doctype: Article src: R language: English refInfo: copyright: @attributes: flag: N holdings: @attributes: islocal: N |
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