Preliminary evidence of improved verbal working memory performance and normalization of task-related frontal lobe activation in schizophrenia following cognitive exercises.
|WbObjective:[|WB] The authors' goal was to evaluate the possibility of treating brain and behavioral aspects of verbal memory dysfunction in patients with schizophrenia through cognitive exercises. |WbMethod:[|WB] Eight patients did daily verbal memory exercises that became progressively more dif...
| Publicado en: | American Journal of Psychiatry Vol. 157; no. 10; pp. 1694 - 1698 |
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| Autores principales: | , , |
| Formato: | Artículo |
| Publicado: |
American Psychiatric Publishing, Inc.
October 2000
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| Materias: | |
| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ssf&AN=513024649&site=ehost-live header: @attributes: shortDbName: ssf uiTerm: 513024649 longDbName: Social Sciences Full Text (H.W. Wilson) uiTag: AN controlInfo: bkinfo: jinfo: jid: 0002953X API jtl: American Journal of Psychiatry issn: 0002953X maglogo: N pubinfo: dt: October 2000 vid: 157 iid: 10 pid: 37323 pub: American Psychiatric Publishing, Inc. artinfo: ui: 513024649 10.1176/appi.ajp.157.10.1694 ppf: 1694 ppct: 4 formats: tig: atl: Preliminary evidence of improved verbal working memory performance and normalization of task-related frontal lobe activation in schizophrenia following cognitive exercises. aug: au: Wexler, Bruce E. Anderson, Margot Fulbright, Robert K. su: Short-term memory Frontal lobe Schizophrenia Brain function localization sug: subj: Short-term memory Frontal lobe Schizophrenia Brain function localization ab: |WbObjective:[|WB] The authors' goal was to evaluate the possibility of treating brain and behavioral aspects of verbal memory dysfunction in patients with schizophrenia through cognitive exercises. |WbMethod:[|WB] Eight patients did daily verbal memory exercises that became progressively more difficult over a 10-week training period. Memory performance and regional brain activations during a verbal memory task were assessed before and after these exercises. |WbResults:[|WB] Verbal but not nonverbal memory performance improved after training; three patients made substantial gains, and five showed little change. Performance gains were correlated with increases in task-related activation of the left inferior frontal cortex. One patient given 5 extra weeks of training 6 weeks after the initial training period showed maintenance of initial performance gains 6 weeks after training, further improvement after the second period of training, and normalization of task-related activation of the left inferior frontal cortex. |WbConclusions:[|WB] Verbal memory deficits can be ameliorated by memory exercises in some patients with schizophrenia. Performance improvements are associated with increased task-related activation of the same brain region that is activated during verbal memory tasks in healthy individuals. Reprinted by permission of the publisher. pubtype: Academic Journal doctype: Article src: R language: English refInfo: copyright: @attributes: flag: N holdings: @attributes: islocal: N |
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