Response-monitoring dysfunction in schizophrenia: an event-related brain potential study.
Error-monitoring abnormalities may underlie positive symptoms of schizophrenia. Response-synchronized event-related potentials during picture—word matching yielded error- and correct-response-related negativity (ERN, CRN) and positivity (Pe, Pc) and preresponse lateralized readiness potentials (LRP)...
| Publicado en: | Journal of Abnormal Psychology Vol. 111; no. 1; pp. 22 - 42 |
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| Autores principales: | , , |
| Formato: | Artículo |
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American Psychological Association
February 2002
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ssf&AN=513129501&site=ehost-live header: @attributes: shortDbName: ssf uiTerm: 513129501 longDbName: Social Sciences Full Text (H.W. Wilson) uiTag: AN controlInfo: bkinfo: jinfo: jid: 0021843X JAP jtl: Journal of Abnormal Psychology issn: 0021843X maglogo: N pubinfo: dt: February 2002 vid: 111 iid: 1 pid: 34 pub: American Psychological Association artinfo: ui: 513129501 10.1037/0021-843X.111.1.22 ppf: 22 ppct: 20 formats: tig: atl: Response-monitoring dysfunction in schizophrenia: an event-related brain potential study. aug: au: Mathalon, Daniel H. Fedor, Mark Faustman, William O. su: Schizophrenia Self-monitoring (Psychology) Electroencephalography Brain function localization sug: subj: Schizophrenia Self-monitoring (Psychology) Electroencephalography Brain function localization ab: Error-monitoring abnormalities may underlie positive symptoms of schizophrenia. Response-synchronized event-related potentials during picture—word matching yielded error- and correct-response-related negativity (ERN, CRN) and positivity (Pe, Pc) and preresponse lateralized readiness potentials (LRP) from 18 schizophrenic patients and 18 controls. Both groups responded faster to matches than nonmatches, although patients were generally slower and made more errors to nonmatches. Compared with controls, patients, particularly with paranoid subtype, had smaller ERNs and larger CRNs, which were indistinguishable. LRPs showed evidence of more response conflict before errors than before correct responses in controls but not patients. Despite ERN/CRN abnormalities, post-error slowing and Pe were normal in patients, suggesting a dissociation of ERN and error awareness. Anterior cingulate and dorsolateral prefrontal cortical dysfunction in schizophrenia are implicated. Reprinted by permission of the publisher. pubtype: Academic Journal doctype: Article src: R language: English refInfo: copyright: @attributes: flag: N holdings: @attributes: islocal: N |
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