Differences in the functional neuroanatomy of inhibitory control across the adult life span.
Inhibitory control, the ability to suppress irrelevant or interfering stimuli, is a fundamental cognitive function that deteriorates during aging, but little is understood about the bases of decline. Thus, we used event-related functional magnetic resonance imaging (fMRI) to study inhibitory control...
| Publicado en: | Psychology & Aging Vol. 17; no. 1; pp. 56 - 72 |
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| Autores principales: | , , |
| Formato: | Artículo |
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American Psychological Association
March 2002
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ssf&AN=513131081&site=ehost-live header: @attributes: shortDbName: ssf uiTerm: 513131081 longDbName: Social Sciences Full Text (H.W. Wilson) uiTag: AN controlInfo: bkinfo: jinfo: jid: 08827974 PYG jtl: Psychology & Aging issn: 08827974 maglogo: N pubinfo: dt: March 2002 vid: 17 iid: 1 pid: 34 pub: American Psychological Association artinfo: ui: 513131081 10.1037/0882-7974.17.1.56 ppf: 56 ppct: 16 formats: tig: atl: Differences in the functional neuroanatomy of inhibitory control across the adult life span. aug: au: Nielson, Kristy A. Langenecker, Scott A. Garavan, Hugh su: Response inhibition Brain -- Imaging Age factors in cognition Brain function localization sug: subj: Response inhibition Brain -- Imaging Age factors in cognition Brain function localization ab: Inhibitory control, the ability to suppress irrelevant or interfering stimuli, is a fundamental cognitive function that deteriorates during aging, but little is understood about the bases of decline. Thus, we used event-related functional magnetic resonance imaging (fMRI) to study inhibitory control in healthy adults aged 18 to 78. Activation during “successful inhibition” occurred predominantly in right prefrontal and parietal regions and was more extensive, bilaterally and prefrontally, in the older groups. Presupplementary motor area was also more active in poorer inhibitory performers. Therefore, older adults activate areas that are comparable to those activated by young adults during inhibition, as well as additional regions. The results are consistent with a compensatory interpretation and extend the aging neuroimaging literature into the cognitive domain of inhibition. Reprinted by permission of the publisher. pubtype: Academic Journal doctype: Article src: R language: English refInfo: copyright: @attributes: flag: N holdings: @attributes: islocal: N |
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